This review will focus on the main lines of evidence that suggest the existence of multiple
types of dopamine D-2 receptors. Dopamine D-2 receptors share structural elements …

The advances in molecular biology in the last decade have provided new insights into the
mechanisms of various diseases via the isolation and cloning of subtypes of G-protein …

The dopamine D2 receptor belongs to the family of seven transmembrane domain G-protein-
coupled receptors and is highly expressed in the central nervous system and the pituitary …

Publisher Summary Studies have investigated several structural variations of the receptor in
more detail to gain insight into the structure and structure–function relationship of Dopamine …

Dopamine is an important neurotransmitter involved in motor control, endocrine function,
reward, cognition and emotion. Dopamine receptors belong to the superfamily of G protein …

A substantial body of evidence shows the capacity of the dopamine D3 receptor to couple
functionally to G proteins when expressed in an appropriate milieu in heterologous …

Publisher Summary he D2-like subfamily of dopamine receptors is a target for drugs used to
treat Parkinson's disease and schizophrenia. Dopamine receptors regulate ion channels to …

Before 1990, the multiplicity of dopamine receptors beyond D1 and D2 had remained a
controversial concept, despite its substantial clinical implications, at a time when it was …

Ten years ago, only two different dopamine receptor subtypes were definitively known to
exist: the D, receptor, linked to the stimulation of adenylyl cyclase, and the D2 receptor which …

Among dopamine receptors, the function and properties of the D3 receptor subtype are
poorly understood. Here we report the identification and characterization of two unique …