Within the basal ganglia, acetylcholine and dopamine play a central role in the
extrapyramidal control of motor function. The physiologic effects of these neurotransmitters …

Neurons expressing the m1, m2, and m4 muscarinic receptor genes in the adult rat striatum
were identified and characterized by using several in situ hybridization and …

The regional distribution of mRNA coding for the m5 muscarinic acetylcholine receptor
subtype was investigated in tissue sections of rat brain by in situ hybridization …

Large families of genetically distinct G‐protein coupled receptor subtypes mediate
dopamine's (D1–D5) and acetylcholine's effects (m1–m5). A functional balance of dopamine …

The existence of four distinct muscarinic acetylcholine receptor genes (m1–m4) has recently
been demonstrated. cDNAs for three of these receptors have been cloned from brain (m1 …

The goal of the present study was to identify the cells containing mRNA coding for the m2
subtype of muscarinic cholinergic receptors in the rat brain. In situ hybridization …

A family of 4 rat muscarinic receptors (m1, m2, m3, and m4) have recently been cloned and
sequenced (Bonner et al., 1987). Since pharmacological probes that are presently available …

SUMMARY A portion of the cDNA sequence corresponding to the third intracellular loop of
either the m4 or m5 muscarinic cholinergic receptor was ligated into the pRIT23 or pET-3a …

Muscarinic ACh receptors mediate complex and clinically important effects in the striatum.
To better understand the roles of the different muscarinic receptor subtypes (m1-m4), we …

Muscarinic m1 receptors traditionally are considered to be postsynaptic to cholinergic fibers,
while m2 receptors are largely presynaptic receptors associated with axons. We have …