Expression of mRNAs that encode D2 dopamine receptor subtypes: anatomical, developmental, and pharmacological studies

AJ MacLennan, GD Frantz, RC Weatherwax… - Molecular and Cellular …, 1990 - Elsevier
We used oligonucleotide probes to isolate cDNAs that encode two subtypes of D2 dopamine
receptors (“D2 long” and “D2 short”). In situ hybridization histochemistry with cRNA probes …

Increased abundance of alternatively spliced forms of D2 dopamine receptor mRNA after denervation.

KA Neve, RL Neve, S Fidel… - Proceedings of the …, 1991 - National Acad Sciences
The existence of two molecular forms of D2 dopamine receptors suggests that differences in
the distribution or regulation of the two forms could be exploited for the pharmacological …

Rat striatal and mesencephalic neurons contain the long isoform of the D2 dopamine receptor mRNA

C Le Moine, B Bloch - Molecular brain research, 1991 - Elsevier
Cloning of the D 2 dopamine receptor gene has demonstrated that two D 2 mRNA isoforms
are generated through alternative splicing: a short mRNA (D 2 415) and a long one (D 2 …

D1 and D2 dopamine receptor mRNA in rat brain.

DM Weiner, AI Levey, RK Sunahara… - Proceedings of the …, 1991 - National Acad Sciences
Physiological and pharmacological criteria have divided dopamine receptors into D1 and
D2 subtypes, and genes encoding these subtypes have recently been cloned. Based on the …

Localization of D1 dopamine receptor mRNA in brain supports a role in cognitive, affective, and neuroendocrine aspects of dopaminergic neurotransmission.

RT Fremeau Jr, GE Duncan… - Proceedings of the …, 1991 - National Acad Sciences
Expression of a D1 dopamine receptor was examined in the rat brain by using a
combination of in situ hybridization and in vitro receptor autoradiography. Cells expressing …

The distribution of a dopamine D2 receptor mRNA in rat brain

DM Weiner, MR Brann - FEBS letters, 1989 - Wiley Online Library
Based on the recently reported sequence of a dopamine D2 receptor cloned from rat brain,
we prepared a series of cDNA probes to determine the distribution of mRNA encoding this …

Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA

ML Bouthenet, E Souil, MP Martres, P Sokoloff, B Giros… - Brain research, 1991 - Elsevier
The messenger RNA (mRNA) of the recently characterized D 3 dopamine receptor was
visualized on rat brain sections using in situ hybridization with a 32 P-labeled ribonucleic …

Differential expression of dopaminergic D2 receptor messenger RNAs during development

KJ Mack, KL O'Malley, RD Todd - Developmental brain research, 1991 - Elsevier
To define the possible roles of multiple types of dopamine D 2 receptors, mRNA levels for
two forms of D 2 receptor were determined during a variety of developmental stages …

D1 and D2 dopamine receptor gene expression in the rat striatum: sensitive cRNA probes demonstrate prominent segregation of D1 and D2 mRNAs in distinct …

C Le Moine, B Bloch - Journal of Comparative Neurology, 1995 - Wiley Online Library
The postsynaptic effects of dopamine in the striatum are mediated mainly by receptors
encoded by D1, D2, and D3 dopamine receptor genes. The D1 and D2 genes are the most …

Localization of the mRNAs for Two Dopamine D2 Receptor Isoforms in the Rat Brain

Y Fujiwara, I Sora, H Tomita, K Akiyama… - Psychiatry and …, 1991 - Wiley Online Library
Two molecular forms of the dopamine D., receptor were generated by alternative RNA
splicing. To investigate the relative distributions of the two mRNAs encoding the D2 receptor …