Effect of angiotensin converting enzyme inhibition on pressure-induced left ventricular hypertrophy in rats.

W Zierhut, HG Zimmer, AM Gerdes - Circulation research, 1991 - Am Heart Assoc
The influence of angiotensin converting enzyme inhibition on the development of left
ventricular (LV) hypertrophy due to stenosis of the aortic arch was studied in female Sprague …

[引用][C] Effects of long-term angiotensin converting enzyme inhibition on myocardial hypertrophy in experimental aortic stenosis in the rat

EP Kromer, GAJ Riegger - The American journal of cardiology, 1988 - Elsevier
FlGUREl. LeR-daorBcm inananimd6 weeksafterinductknofexperimentdaor6c~. effects are
not the only determinants for regression of LV hypertrophy. Other factors such as …

Exacerbation of left ventricular ischemic diastolic dysfunction by pressure-overload hypertrophy. Modification by specific inhibition of cardiac angiotensin converting …

FR Eberli, CS Apstein, S Ngoy, BH Lorell - Circulation research, 1992 - Am Heart Assoc
Hearts with compensatory pressure-overload hypertrophy show an increased intracardiac
activation of angiotensin II that may contribute to ischemic diastolic dysfunction. We studied …

Differential effects of angiotensin II receptor blockade on pressure-induced left ventricular hypertrophy and fibrosis in rats

HA Baba, T Iwai, M Bauer, M Irlbeck, KW Schmid… - Journal of molecular and …, 1999 - Elsevier
The effects of the angiotensin II receptor type 1 (AT1) antagonist losartan on pressure
overload-induced left ventricular (LV) hypertrophy were studied in female Sprague–Dawley …

Role of Angiotensin in Pressure Overload-Induced Hypertrophy in Rats: Effects of Angiotensin-Converting Enzyme Inhibitors, an AT: 1: Receptor Antagonist, and …

R Mohabir, SD Young… - Journal of cardiovascular …, 1994 - journals.lww.com
The renin-angiotensin system (RAS) has been proposed to play a major role in causing the
heart to hypertrophy during pressure overload. We examined whether blockade of this …

Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance …

H Schunkert, VJ Dzau, SS Tang… - The Journal of …, 1990 - Am Soc Clin Investig
We compared the activity and physiologic effects of cardiac angiotensin converting enzyme
(ACE) using isovolumic hearts from male Wistar rats with left ventricular hypertrophy due to …

Role of neurohumoral systems for pressure induced left ventricular hypertrophy in experimental supravalvular aortic stenosis in rats

EP Kromer, D Eisner… - American journal of …, 1991 - academic.oup.com
We studied the role of the sympathetic nervous system and the renin angiotensin system for
pressure induced left ventricular hypertrophy (LVH) in 135 rats with experimental …

Angiotensin-converting enzyme inhibition prolongs survival and modifies the transition to heart failure in rats with pressure overload hypertrophy due to ascending …

EO Weinberg, FJ Schoen, D George, Y Kagaya… - Circulation, 1994 - Am Heart Assoc
BACKGROUND We tested the hypotheses that long-term administration of the angiotensin-
converting enzyme (ACE) inhibitor fosinopril will regress hypertrophy, modify the transition to …

Blockade of the renin-angiotensin system in cardiac pressure-overload hypertrophy in rats

G Bruckschlegel, SR Holmer, K Jandeleit, D Grimm… - …, 1995 - Am Heart Assoc
Left ventricular hypertrophy in response to pressure overload may be modified by
neurohumoral activation. To investigate the contribution of the renin-angiotensin system, we …

Cardiac remodeling and angiotensin II-forming enzyme activity of the left ventricle in hamsters with chronic pressure overload induced by ascending aortic stenosis

M Shimizu, R Tanaka, T Fukuyama, R Aoki… - Journal of Veterinary …, 2006 - jstage.jst.go.jp
Cardiac remodeling and angiotensin II-forming enzyme activity of the left ventricle on chronic
pressure overload were studied in male Syrian hamsters, whose chymase activity is similar …