Effects of radiation therapy on adult brain behavior: evidence for a rebound phenomenon in a phase 1 trial

C Armstrong, J Mollman, BW Corn, J Alavi… - Neurology, 1993 - AAN Enterprises
Although radiotherapy (XRT) is a necessary course of treatment to prolong life expectancy in
patients with many types of brain neoplasms, it has damaging effects that are little …

[PDF][PDF] Radiotherapeutic effects on brain function: double dissociation of memory systems

AA Pruitt, JE Mollman, PC Phillips - … , and behavioral neurology, 2000 - researchgate.net
Objective: The neurocognitive sequelae of therapeutic cranial irradiation are not well
characterized in adults with primary brain tumors. To address this problem, we prospectively …

A longitudinal neuropsychological study of partial brain radiation in adults with brain tumors

IJ Torres, AJ Mundt, PJ Sweeney, S Llanes–Macy… - Neurology, 2003 - AAN Enterprises
Objective: To investigate longitudinal cognitive functioning in patients with brain tumor
treated with modern highly conformal fractionated partial brain radiation therapy (RT) …

Cognitive sequelae of brain radiation in adults

NN Laack, PD Brown - Seminars in oncology, 2004 - Elsevier
Radiotherapy (RT) is a proven curative and palliative therapeutic tool in the treatment of a
wide variety of primary and metastatic brain tumors in adults. Recent advances in …

Neuropsychological impact of treatment of brain tumors

CR De Luca, R Conroy, MC McCarthy… - Late effects of treatment …, 2009 - Springer
Advances in treatments for brain tumors have seen a significant increase in survival rates
over the past few decades. This increase has been particularly dramatic in the pediatric …

Short‐term effects of radiotherapy on attention and memory performances in patients with brain tumors

AM Lilja, RI Portin, PI Hämäläinen, EK Salminen - Cancer, 2001 - Wiley Online Library
BACKGROUND The objective of the current study was to evaluate the short‐term effects of
radiotherapy on attention and memory performance in patients with brain tumors. METHODS …

Biphasic patterns of memory deficits following moderate-dose partial-brain irradiation: neuropsychologic outcome and proposed mechanisms.

C Armstrong, J Ruffer, B Corn, K DeVries… - Journal of clinical …, 1995 - ascopubs.org
PURPOSE To identify the longitudinal neurobehavioral characteristics of the early-delayed
and late-delayed effects of partial-brain radiotherapy for patients with supratentorial brain …

Long-term cognitive dysfunction after radiation therapy for primary brain tumors

L Haldbo-Classen, A Amidi, LM Wu, S Lukacova… - Acta …, 2019 - Taylor & Francis
Background: The extent of radiation therapy (RT)-induced changes in cognitive function is
unknown. RT with protons instead of photons spares the healthy brain tissue more and is …

Late cognitive and radiographic changes related to radiotherapy: initial prospective findings

CL Armstrong, JV Hunter, GE Ledakis, B Cohen… - Neurology, 2002 - AAN Enterprises
Background: Assumptions about the damaging effects of radiotherapy (XRT) are based on
studies in which total dose, dose fraction, treatment volume, degree of malignancy …

The early effects of radiotherapy on intellectual and cognitive functioning in patients with frontal brain tumours: the use of a new neuropsychological methodology

A Costello, T Shallice, R Gullan, R Beaney - Journal of neuro-oncology, 2004 - Springer
Investigations of the effects of radiation on neuropsychological functions have revealed
variable outcomes, ranging from no effect to severe cognitive impairment. However, many of …