Bezafibrate therapy in patients with isolated low high-density lipoprotein cholesterol levels may have a beneficial effect in prevention of atherosclerosis

MS Weintraub, I Grosskopf, G Charach, R Mor… - Metabolism, 1995 - Elsevier
Although a low plasma high-density lipoprotein cholesterol (HDL-C) level is a well-accepted
risk factor for coronary artery disease (CAD), it is unclear whether pharmacologic agents can …

Long-term efficacy of bezafibrate in reduction of small, dense low-density lipoprotein by hypotriglyceridemic action

T Hirano, T Kazumi, G Yoshino - Current therapeutic research, 2000 - Elsevier
OBJECTIVE: We examined both the effects of long-term bezafibrate treatment on low-density
lipoprotein (LDL) particle size in hyperlipidemic patients and the relationship between …

Relation between on-treatment increments in serum high-density lipoprotein cholesterol levels and cardiac mortality in patients with coronary heart disease (from the …

I Goldenberg, U Goldbourt, V Boyko, S Behar… - The American journal of …, 2006 - Elsevier
This study evaluated the association between changes in serum levels of high-density
lipoprotein (HDL) cholesterol that occur under bezafibrate therapy and cardiac mortality in …

Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease

BIP Study Group - Circulation, 2000 - cir.nii.ac.jp
抄録< jats: p>< jats: italic> Background</jats: italic>—Coronary heart disease patients with
low high-density lipoprotein cholesterol (HDL-C) levels, high triglyceride levels, or both are …

Dose-response study of bezafibrate on serum lipoprotein concentrations in hyperlipoproteinaemia

AG Olsson, PD Lang - Atherosclerosis, 1978 - Elsevier
The effect of bezafibrate in the dosages 450, 900 and 1350 mg daily on serum lipoprotein
concentrations were studied in 20 subjects with primary hyperlipoproteinaemia (16 of type …

Effect of bezafibrate treatment on the altered lipoprotein profiles in hypertriglyceridemic subjects

M Norioka, M Suzuki, K Ryomoto… - … of atherosclerosis and …, 2000 - jstage.jst.go.jp
The effects of bezafibrate treatment on lipoprotein metabolism were investigated in
hypertriglyceridemic subjects. Bezafibrate, a fibric acid derivative, was administered at 200 …

Baseline characteristics of patients participating in the Bezafibrate Infarction Prevention (BIP) Study.

U Goldbourt, D Brunner, S Behar… - European heart …, 1998 - europepmc.org
Low high density lipoprotein (HDL) cholesterol, elevated triglycerides, or a combination of
both, carries an increased risk of coronary heart disease (CHD). The benefit of therapy that …

Determinants of Bezafibrate-induced Improvements in LDL Cholesterol in Dyslipidemic Patients with Diabetes A Subgroup Analysis of the J-BENEFIT Study

T Hirose, T Teramoto, K Abe, T Taneyama… - … of Atherosclerosis and …, 2015 - jstage.jst.go.jp
Aim: Our previous “J-BENEFIT (Japan BEzafibrate cliNical EFfectIveness and Tolerability)”
study demonstrated that bezafibrate improves blood lipid profiles and glucose control in …

Atherogenic risk reduction in patients with dyslipidaemia comparison between bezafibrate and lovastatin

H Sinzinger, C Pirich, P Kondor, H Etti - European heart journal, 1995 - academic.oup.com
Objective: To examine the atherogenic risk-reducing effect of bezafibrate and lovastatin.
Design, setting, patients, interventions: Double-blind, randomized clinical trial of male and …

Long-term benefit of high-density lipoprotein cholesterol–raising therapy with bezafibrate: 16-year mortality follow-up of the bezafibrate infarction prevention trial

I Goldenberg, V Boyko, A Tennenbaum… - Archives of internal …, 2009 - jamanetwork.com
Background Major randomized trials of fibrate therapy demonstrate an inverse relationship
between on-treatment high-density lipoprotein cholesterol (HDL-C) increments and clinical …