Ito cells, perisinusoidal mesenchymal elements with possible pericytic functions within the
liver, recently have been shown to play multiple physiological and pathophysiological roles …

Irecent years we have witnessed a dramatic increase in our knowledge of the characteristics
and functions of liver nonparenchymal cells. In particular, much attention has been focussed …

To identify Ito cells in normal and pathological adult human livers, immunohistochemical
studies were performed by the avidin-biotin-peroxidase complex method using monoclonal …

Hepatic stellate cells (HSCs), also referred to as Ito cells, perisinusiodal cells and fat-storing
cells, have numerous vital functions. They are the main extracellular matrix-producing cells …

Hepatic stellate cells (HSCs), also called Ito cells or lipocytes, are vitamin A-storing cells
located in the Dissé space between hepatocytes and sinusoidal endothelial cells. Upon liver …

Activation of liver Ito cells is characterized by increased proliferation, fibrogenesis, loss of
cellular retinoid and change of cell-shape. Here, we have described fundamental …

Perisinusoidal cells (PSCs) are currently regarded as the major source of extracellular
matrix proteins during hepatic fibrogenesis in response to liver injury. However, the cellular …

While Ito cells appear to be a major source of increased matrix synthesis during hepatic
fibrogenesis, the cellular changes that occur in these cells during liver fibrosis have not been …

Hepatic lipocytes (perisinusoidal, Ito cells) are the primary matrix–producing cells in liver
fibrosis. During liver injury they undergo activation, a process characterized by cell …

Hepatic stellate cell (also referred to as Ito cell, fat-storing cell, perisinusoidal cell, lipocyte) is
one of the sinusoid-constituent cells that play multiple roles in liver pathophysiology …