The PU. 1 protein is an ets-related transcription factor that is expressed in macrophages and
B lymphocytes. We present evidence that PU. 1 binds to the promoter of the I-Aβ gene, ie a …

We have previously identified and characterized the macrophage-, neutrophil-and B cell-
specific nuclear factor βA (NFβA), which is involved in transcriptional regulation of the …

The B-lymphocyte-and macrophage-specific transcription factor PU. 1 is a member of the ets
family of proteins. To understand how PU. 1 functions as a transcription factor, we initiated a …

PU. 1 is a B-cell-and macrophage-specific transcription factor. By an electrophoretic mobility
shift assay and dimethyl sulfate methylation interference assays, we show that PU. 1 binds to …

PU. 1 is a transcription factor that belongs to the ets family of DNA binding proteins. In this
study, we show by Far Western blot analyses that multiple nuclear proteins are capable of …

The DNA-binding protein PU. 1 is a myeloid lineage–determining and pioneering
transcription factor due to its ability to bind" closed" genomic sites and maintain" open" …

PU. 1 is a tissue-specific transcription factor that is expressed in cells of the hematopoietic
lineage including macrophages, granulocytes, and B lymphocytes. Bone marrow-derived …

Regulation of the hematopoietic transcription factor PU. 1 (Spi-1) plays a critical role in the
development of white cells, and abnormal expression of PU. 1 can lead to leukemia. We …

Numerous macrophage-restricted promoters lack TATA boxes or other conventional
initiation motifs but contain high affinity binding sites (PU boxes) for the macrophage …

We have isolated a cDNA clone, PU. l, that codes for a new tissue-specific DNA binding
protein. Analysis of the binding site by methylatlon Interference and DNA-ase I protection …