Irecent years we have witnessed a dramatic increase in our knowledge of the characteristics
and functions of liver nonparenchymal cells. In particular, much attention has been focussed …

It is generally accepted that the perisinusoidal hepatic stellate cell (HSC), a liver specific
type of pericytes (previously termed fat-or vitamin A–storing cell, Ito cell) localized in close …

In recent years it has been recognized that hepatic stellate cells play a fundamental role in
normal hepatic physiology and in the pathophysiology of liver injury. This is due, in part, to …

T” RESPONSE to tissue injury comprises a series of events which are relatively similar
irrespective of the tissue involved, although each organ contains specialized cells and …

Hepatic stellate cell (also referred to as Ito cell, fat-storing cell, perisinusoidal cell, lipocyte) is
one of the sinusoid-constituent cells that play multiple roles in liver pathophysiology …

Hepatic stellate cells (HSCs), also referred to as Ito cells, perisinusiodal cells and fat-storing
cells, have numerous vital functions. They are the main extracellular matrix-producing cells …

Hepatic stellate cells (HSCs) were identified by Boll and Von Kupffer in the 1870s. They
were subsequently largely ignored until 1952, when Ito and Nemeto1 described their …

Hepatic stellate cells (HSCs), a mesenchymal cell type in hepatic parenchyma, have unique
features with respect to their cellular origin, morphology, and function. Normal, quiescent …

The accumulation of extracellular matrix observed in fibrosis and cirrhosis is due to the
activation of fibroblasts, which acquire a myofibroblastic phenotype. Myofibroblasts, which …

Hepatic stellate cells (HSCs) are pericytes of liver in the space between parenchymal cells
and sinusoidal endothelial cells of the hepatic lobule. HSCs comprise specialized functions …