Estrogen receptor-induced DNA bending: orientation of the bend and replacement of an estrogen response element with an intrinsic DNA bending sequence.
AM Nardulli, C Grobner, D Cotter - Molecular Endocrinology, 1995 - academic.oup.com
The estrogen receptor (ER) binds to DNA fragments containing estrogen response elements
(EREs) and causes them to bend. To characterize this ER-induced DNA bend and …
(EREs) and causes them to bend. To characterize this ER-induced DNA bend and …
Human estrogen receptor bound to an estrogen response element bends DNA.
AM Nardulli, GL Greene, DJ Shapiro - Molecular Endocrinology, 1993 - academic.oup.com
We have used gel mobility shift assays to examine changes in DNA bending induced by
binding of human estrogen receptor (hER) to a series of estrogen response element (ERE) …
binding of human estrogen receptor (hER) to a series of estrogen response element (ERE) …
Effects of wild type and mutant estrogen receptors on DNA flexibility, DNA bending, and transcription activation.
SJ Potthoff, LE Romine, AM Nardulli - Molecular Endocrinology, 1996 - academic.oup.com
We examined the ability of wild type (WT) estrogen receptor (ER) and mutant ERs to induce
distortion and directed bends in DNA fragments containing estrogen response elements and …
distortion and directed bends in DNA fragments containing estrogen response elements and …
DNA bending by nuclear receptors.
AM Nardulli, DJ Shapiro - Receptor, 1993 - europepmc.org
Although steroid hormone receptors constitute an intensively studied family of ligand-
regulated transcription factors, the mechanism by which these receptors activate …
regulated transcription factors, the mechanism by which these receptors activate …
Differential modulation of DNA conformation by estrogen receptors α and β
JR Schultz, MA Loven, VMS Melvin, DP Edwards… - Journal of Biological …, 2002 - ASBMB
The human estrogen receptor (ER) induces transcription of estrogen-responsive genes
upon binding to estrogen and the estrogen response element (ERE). To determine whether …
upon binding to estrogen and the estrogen response element (ERE). To determine whether …
Binding of the estrogen receptor DNA-binding domain to the estrogen response element induces DNA bending
AM Nardulli, DJ Shapiro - Molecular and cellular biology, 1992 - Taylor & Francis
We have used circular permutation analysis to determine whether binding of purified
Xenopus laevis estrogen receptor DNA-binding domain (DBD) to a DNA fragment …
Xenopus laevis estrogen receptor DNA-binding domain (DBD) to a DNA fragment …
Prebending the estrogen response element destabilizes binding of the estrogen receptor DNA binding domain
J Kim, G De Haan, AM Nardulli… - Molecular and cellular …, 1997 - Am Soc Microbiol
Binding of many eukaryotic transcription regulatory proteins to their DNA recognition
sequences results in conformational changes in DNA. To test the effect of altering DNA …
sequences results in conformational changes in DNA. To test the effect of altering DNA …
Progesterone receptor-induced bending of its target DNA: distinct effects of the A and B receptor forms.
P Prendergast, Z Pan, DP Edwards - Molecular Endocrinology, 1996 - academic.oup.com
We have used circular permutation and phasing electrophoretic mobility shift assays to
determine the ability of the A and B forms of human progesterone receptor (PR) to bend …
determine the ability of the A and B forms of human progesterone receptor (PR) to bend …
Estrogen receptor affinity and location of consensus and imperfect estrogen response elements influence transcription activation of simplified promoters.
AM Nardulli, LE Romine, C Carpo… - Molecular …, 1996 - academic.oup.com
We have examined the ability of estrogen receptor (ER) to bind and bend DNA fragments
containing the Xenopus laevis vitellogenin A2 estrogen response element (ERE), which …
containing the Xenopus laevis vitellogenin A2 estrogen response element (ERE), which …
[HTML][HTML] Localization of curved DNA and its association with nucleosome phasing in the promoter region of the human estrogen receptor α gene
We determined DNA bend sites in the promoter region of the human estrogen receptor (ER)
gene by the circular permutation assay. A total of five sites (ERB− 4 to− 1, and ERB+ 1) …
gene by the circular permutation assay. A total of five sites (ERB− 4 to− 1, and ERB+ 1) …