Gel entrapment and micro-encapsulation: Methods, applications and engineering principles

RG Willaert, GV Baron - Reviews in chemical engineering, 1996 - degruyter.com
Methods, modelling and applications of gel immobilisation and micro-encapsulation of living
cells are reviewed. These two methods are most frequently used as they allow for excellent …

Cell immobilization and its applications in biotechnology: current trends and future prospects

RG Willaert - Fermentation Microbiology and Biotechnology …, 2018 - taylorfrancis.com
The adsorption of cells to an organic or inorganic support material is achieved via the Van
der Waals forces and ionic interactions. When cells are encapsulated in an immobilized cell …

Scale-up of gel bead and microcapsule production in cell immobilization

D Poncelet, B Poncelet De Smet… - … of animal cell …, 1993 - books.google.com
Immobilization systems compatible with many biocatalysts have involved the use of various
gel-forming proteins (gelatin), polysaccharides (agar, calcium alginate, and к-carrageenan) …

The interphase technique: a simple method of cell immobilization in gel-beads

A López, N Lázaro, AM Marqués - Journal of microbiological methods, 1997 - Elsevier
A variation of the emulsion techniques for microbial cell immobilization by encapsulation in
gel beads is described. The utilized gels are silica gel or natural polymers like agar …

Microencapsulation of Langerhans islets in agarose microbeads and their application for a bioartificial pancreas

H Iwata, H Amemiya, T Matsuda… - Journal of bioactive …, 1988 - journals.sagepub.com
Microencapsulation of islets is considered to be a promising approach to the development of
a bioartificial pancreas. In this study agarose was examined as a material to …

A three-dimensional microfluidic approach to scaling up microencapsulation of cells

S Tendulkar, SH Mirmalek-Sani, C Childers… - Biomedical …, 2012 - Springer
Current applications of the microencapsulation technique include the use of encapsulated
islet cells to treat Type 1 diabetes, and encapsulated hepatocytes for providing temporary …

A versatile alginate droplet generator applicable for microencapsulation of pancreatic islets

GHJ Wolters, WM Fritschy, D Gerrits… - Journal of applied …, 1992 - Wiley Online Library
Alginate beads for immunoisolation of pancreatic islets by microencapsulation should be
small, smooth, and spherical in order to ensure that around the islets a strong alginate …

A scalable microfluidic device for the mass production of microencapsulated islets

S Tendulkar, JP McQuilling, C Childers… - Transplantation …, 2011 - Elsevier
The objective of this research was to test the viability and function of islets
microencapsulated using a scalable microfluidic device that is suitable for the mass …

Microencapsulation of crystalline insulin or islets of Langerhans: an insulin diffusion study

YF Leung, GM O'Shea, MFA Goosen, AM Sun - Artificial organs, 1983 - Wiley Online Library
Microcapsules containing insulin crystals or islets of Langerhans were made by extruding a
mixture of insulin crystals or islets and sodium alginate into a calcium chloride solution, and …

Entrapment of dispersed pancreatic islet cells in CultiSpher‐S macroporous gelatin microcarriers: Preparation, in vitro characterization, and microencapsulation

S Del Guerra, C Bracci, K Nilsson… - Biotechnology and …, 2001 - Wiley Online Library
Immunoprotection of pancreatic islets for successful allo‐or xenotransplantation without
chronic immunosuppression is an attractive, but still elusive, approach for curing type 1 …