The effects of selective genotyping on estimates of proportion of recombination between linked quantitative trait loci

JZ Lin, K Ritland - Theoretical and Applied Genetics, 1996 - Springer
Selective genotyping is the marker assay of only the more extreme phenotypes for a
quantitative trait and is intended to increase the efficiency of quantitative trait loci (QTL) …

Detection and parameter estimation for quantitative trait loci using regression models and multiple markers

Y Da, PM VanRaden, LB Schook - Genetics Selection Evolution, 2000 - Springer
A strategy of multi-step minimal conditional regression analysis has been developed to
determine the existence of statistical testing and parameter estimation for a quantitative trait …

Aspects of maximum likelihood methods for the mapping of quantitative trait loci in line crosses

SA Knott, CS Haley - Genetics Research, 1992 - cambridge.org
Maximum likelihood methods for the mapping of quantitative trait loci (QTL) have been
investigated in an F2 population using simulated data. The use of adjacent (flanking) marker …

Improving quantitative trait loci mapping resolution in experimental crosses by the use of genotypically selected samples

Z Xu, F Zou, TJ Vision - Genetics, 2005 - academic.oup.com
One of the key factors contributing to the success of a quantitative trait locus (QTL) mapping
experiment is the precision with which QTL positions can be estimated. We show, using …

Mapping quantitative trait loci using molecular marker linkage maps

SJ Knapp, WC Bridges, D Birkes - Theoretical and applied genetics, 1990 - Springer
High-density restriction fragment length polymorphism (RFLP) and allozyme linkage maps
have been developed in several plant species. These maps make it technically feasible to …

Sequential quantitative trait locus mapping in experimental crosses

JM Satagopan, S Sen, GA Churchill - Statistical applications in …, 2007 - degruyter.com
The etiology of complex diseases is heterogeneous. The presence of risk alleles in one or
more genetic loci affects the function of a variety of intermediate biological pathways …

Combining different line crosses for mapping quantitative trait loci using the identical by descent-based variance component method

C Xie, DDG Gessler, S Xu - Genetics, 1998 - academic.oup.com
Mapping quantitative trait loci (QTLs) is usually conducted with a single line cross. The
power of such QTL mapping depends highly on the two parental lines. If the two lines are …

Power and precision of alternate methods for linkage disequilibrium mapping of quantitative trait loci

HH Zhao, RL Fernando, JCM Dekkers - Genetics, 2007 - academic.oup.com
Linkage disequilibrium (LD) analysis in outbred populations uses historical recombinations
to detect and fine map quantitative trait loci (QTL). Our objective was to evaluate the effect of …

Efficient marker-based recurrent selection for multiple quantitative trait loci

I Goldringer, S Openshaw - Genetics Research, 2000 - cambridge.org
We studied the efficiency of recurrent selection based solely on marker genotypes (marker-
based selection), in order to increase favourable allele frequency at 50 previously detected …

Fine mapping of quantitative trait loci using linkage disequilibria with closely linked marker loci

THE Meuwissen, ME Goddard - Genetics, 2000 - academic.oup.com
A multimarker linkage disequilibrium mapping method was developed for the fine mapping
of quantitative trait loci (QTL) using a dense marker map. The method compares the …