Rapid internalization of exogenous ganglioside GM3 and its metabolism to ceramide in human myelogenous leukemia HL‐60 cells compared with control ganglioside …

M Nakamura, A Tsunoda, Y Furukawa, T Sakai… - FEBS …, 1997 - Wiley Online Library
Incorporation and metabolism of exogenous GM3 in human myelogenous leukemia HL‐60
cells were analyzed using 3H‐labeled GM3 ([3H] GM3).[3H] GM3 was rapidly internalized …

Ganglioside GM3 Can Induce Megakaryocytoid Differentiation of Human Leukemia Cell Line K562 Cells

M Nakamura, K Kirito, J Yamanoi, T Wainai, H Nojiri… - Cancer research, 1991 - AACR
The role of acidic glycosphingolipids in cell growth and differentiation was investigated
using the multipotent leukemia cell line K562. When GM3 was added to cell culture media …

[HTML][HTML] Uptake and metabolism of exogenous gangliosides by cultured cells: effect of choleragen on the turnover of GM1.

PH Fishman, RM Bradley, BE Hom, J Moss - Journal of Lipid Research, 1983 - Elsevier
When added to the culture medium, 3H-labeled GM1 (tritiated predominantly in the terminal
galactose residue) was taken up by murine NCTC 2071 and rat glioma C6 cells, both of …

Structure of the ceramide moiety of GM1 ganglioside determines its occurrence in different detergent-resistant membrane domains in HL-60 cells

M Panasiewicz, H Domek, G Hoser, M Kawalec… - Biochemistry, 2003 - ACS Publications
To investigate the effect of the ceramide moiety of GM1 ganglioside on its association with
detergent resistant membrane domains (DRMs) in human leukemia HL-60 cells,[3H] labeled …

Density-dependent expression of ganglioside GM3 by human skin fibroblasts in an all-or-none fashion, as a possible modulator of cell growth in vitro

H Rösner, CH Greis, HP Rodemann - Experimental cell research, 1990 - Elsevier
The expression of GM3 In human skin fibroblasts (cell type MF II) was investigated
biochemically and immunochemically by means of the monoclonal antibody M2590. A cell …

Expression of GD3 Ganglioside in Childhood T-Cell Lymphoblastic Malignancies

WD Merritt, JT Casper, SJ Lauer, GH Reaman - Cancer research, 1987 - AACR
Lymphoblasts from seven children with T-cell lymphoblastic malignancies and three children
with non-T, non-B acute lymphoblastic leukemia (ALL) were analyzed for ganglioside …

Incorporation and metabolism of ganglioside GM2 in skin fibroblasts from normal and GM2 gangliosidosis subjects

S Sonderfeld, E Conzelmann… - European journal of …, 1985 - Wiley Online Library
Ganglioside GM2, 3H‐labeled in the sphingoid base, was added to the culture medium of
normal and GM2 gangliosidosis fibroblasts. Ganglioside was found to adsorb rapidly to the …

An acidic glycosphingolipid, monosialo-ganglioside GM3, is a potent physiological inducer for monocytic differentiation of human promyelocytic leukemia cell line HL …

M Saito, Y Terui, H Nojiri - Biochemical and Biophysical Research …, 1985 - Elsevier
A remarkable increase in monosialo-ganglioside GM3 was observed during the monocytic
differentiation of HL-60 cells induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). On …

Endogenously produced ganglioside GM3 endows etoposide and doxorubicin resistance by up-regulating Bcl-2 expression in 3LL Lewis lung carcinoma cells

M Noguchi, K Kabayama, S Uemura, B Kang… - …, 2006 - academic.oup.com
The ganglioside patterns have been shown to dramatically change during cell proliferation
and differentiation and in certain cell-cycle phases, brain development, and cancer …

Incorporation and metabolism of exogenous GM1 ganglioside in rat liver

R Ghidoni, M Trinchera, B Venerando… - Biochemical …, 1986 - portlandpress.com
The pathways of metabolic processing of exogenously administered GM1 ganglioside in rat
liver was investigated at the subcellular level. The GM1 used was 3H-labelled at the level of …