An iron-and fur-repressed Legionella pneumophila gene that promotes intracellular infection and encodes a protein with similarity to the Escherichia coli aerobactin …
EK Hickey, NP Cianciotto - Infection and immunity, 1997 - Am Soc Microbiol
Legionella pneumophila, a parasite of alveolar macrophages, requires iron for intra-and
extracellular growth. Although its mechanisms for iron assimilation are poorly understood …
extracellular growth. Although its mechanisms for iron assimilation are poorly understood …
Cloning and sequencing of the Legionella pneumophila fur gene
EK Hickey, NP Cianciotto - Gene, 1994 - Elsevier
Iron is required for the intracellular and extracellular growth of Legionella pneumophila (Lp).
In addition, variations in iron levels may serve as a signal for changes in gene expression. In …
In addition, variations in iron levels may serve as a signal for changes in gene expression. In …
Legionella pneumophila mutants that are defective for iron acquisition and assimilation and intracellular infection
CD Pope, W O'Connell, NP Cianciotto - Infection and immunity, 1996 - Am Soc Microbiol
Legionella pneumophila, a parasite of macrophages and protozoa, requires iron for optimal
extracellular and intracellular growth. However, its mechanisms of iron acquisition remain …
extracellular and intracellular growth. However, its mechanisms of iron acquisition remain …
The Legionella pneumophila iraAB Locus Is Required for Iron Assimilation, Intracellular Infection, and Virulence
VK Viswanathan, PH Edelstein, CD Pope… - Infection and …, 2000 - Am Soc Microbiol
Legionella pneumophila, a facultative intracellular parasite of human alveolar macrophages
and protozoa, causes Legionnaires' disease. Using mini-Tn 10 mutagenesis, we previously …
and protozoa, causes Legionnaires' disease. Using mini-Tn 10 mutagenesis, we previously …
Legionella pneumophila feoAB Promotes Ferrous Iron Uptake and Intracellular Infection
M Robey, NP Cianciotto - Infection and immunity, 2002 - Am Soc Microbiol
In order to determine the role of ferrous iron transport in Legionella pathogenesis, we
identified and mutated the feoB gene in virulent Legionella pneumophila strain 130b. As it is …
identified and mutated the feoB gene in virulent Legionella pneumophila strain 130b. As it is …
The Cytochrome c Maturation Locus of Legionella pneumophila Promotes Iron Assimilation and Intracellular Infection and Contains a Strain-Specific Insertion …
VK Viswanathan, S Kurtz, LL Pedersen… - Infection and …, 2002 - Am Soc Microbiol
Previously, we obtained a Legionella pneumophila mutant, NU208, that is hypersensitive to
iron chelators when grown on standard Legionella media. Here, we demonstrate that …
iron chelators when grown on standard Legionella media. Here, we demonstrate that …
The Secreted Pyomelanin Pigment of Legionella pneumophila Confers Ferric Reductase Activity
CH Chatfield, NP Cianciotto - Infection and immunity, 2007 - Am Soc Microbiol
The virulence of Legionella pneumophila is dependent upon its capacity to acquire iron. To
identify genes involved in expression of its siderophore, we screened a mutagenized …
identify genes involved in expression of its siderophore, we screened a mutagenized …
A Study of Iron Acquisition Mechanisms of Legionella pneumophila Grown in Chemostat Culture
BW James, WS Mauchline, PJ Dennis, CW Keevil - Current microbiology, 1997 - Springer
We recently demonstrated that the virulence of a clinical isolate of Legionella pneumophila
is significantly attenuated when cultured in an iron-limited environment. In this study the …
is significantly attenuated when cultured in an iron-limited environment. In this study the …
The major iron-containing protein of Legionella pneumophila is an aconitase homologous with the human iron-responsive element-binding protein
JM Mengaud, MA Horwitz - Journal of bacteriology, 1993 - Am Soc Microbiol
Legionella pneumophila has high iron requirements, and its intracellular growth in human
monocytes is dependent on the availability of intracellular iron. To learn more about iron …
monocytes is dependent on the availability of intracellular iron. To learn more about iron …
Analysis of the Legionella pneumophila fliI gene: intracellular growth of a defined mutant defective for flagellum biosynthesis
JJ Merriam, R Mathur, R Maxfield-Boumil… - Infection and …, 1997 - Am Soc Microbiol
Using a PCR-based strategy and degenerate oligonucleotides, we isolated a Legionella
pneumophila gene that showed high sequence similarity to members of the fliI gene family …
pneumophila gene that showed high sequence similarity to members of the fliI gene family …
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