[图书][B] The glucose-regulated proteins: Altered expression in human breast cancer cell lines and applications in cancer gene therapy in an in vivo mouse model …

G Gazit - 1997 - search.proquest.com
The glucose regulated proteins (GRPs) are a family of proteins that are localized to the
lumen of the endoplasmic reticulum (ER). The predominant members of this family are …

[图书][B] Functional analysis of the mammalian glucose-regulated proteins: Normal and reduced expression in in vivo rodent model systems

EB Little - 1996 - search.proquest.com
The glucose regulated proteins (GRPs) are a family of proteins localized to the lumen of the
endoplasmic reticulum. These proteins are induced by a variety of conditions such as …

[图书][B] Using the grp78 and VEGF promoter as components for specific expression in a tumor environment and the effect of genistein treatment on grp78 induction in …

H Ko - 2003 - search.proquest.com
Glucose-regulated proteins (GRPs) are a family of chaperone proteins localized in the
endoplasmic reticulum lumen that allow for cell survival under certain stress conditions …

The glucose-regulated proteins: stress induction and clinical applications

AS Lee - Trends in biochemical sciences, 2001 - cell.com
A protective mechanism used by cells to adapt to stress of the endoplasmic reticulum (ER) is
the induction of members of the glucose-regulated protein (Grp) family. The induction of …

The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications

E Little, M Ramakrishnan, B Roy… - Critical reviews in …, 1994 - dl.begellhouse.com
The glucose-regulated proteins (GRPs) were first described as a set of proteins whose
synthe-sis was enhanced when mammalian cells were deprived of glucose. Subsequently …

[图书][B] Transcriptional regulation of the Grp78 promoter: The role of dexamethasone and GATA transcription factors

WC Tai - 2004 - search.proquest.com
The induction of glucose regulation proteins (GRPs) plays an important role in protecting
cells from endoplasmic reticulum stress that leads to programmed cell death. The induction …

De‐regulation of GRP stress protein expression in human breast cancer cell lines

G Gazit, J Lu, AS Lee - Breast cancer research and treatment, 1999 - Springer
The stress‐inducible glucose regulated proteins (GRPs), a class of calcium‐binding
molecular chaperones localized in the endoplasmic reticulum, have been implicated in the …

Glucose regulated proteins in cancer progression, drug resistance and immunotherapy

Y Fu, AS Lee - Cancer biology & therapy, 2006 - Taylor & Francis
It has been established that as molecular chaperones, the glucose regulated proteins
(GRPs) play an important role in maintaining cellular homeostasis. This conventional …

Molecular Approaches Toward Manipulating the Expression of the Glucose-Regulated Proteins in Mammalian Cells

AS Lee, X Li, L Li, E Little - Cell Biology and Biotechnology: Novel …, 1993 - Springer
Since the discovery of the glucose-regulated proteins (GRPs) in 1977 as a set of mammalian
proteins specifically induced in cultured cells deprived of glucose in their culture medium (1) …

The Role of Glucose-Regulated Proteins in Endometrial and Pancreatic Cancers

J Shen - 2016 - search.proquest.com
The glucose-regulated proteins (GRPs), including GRP78 and GRP94, are stress-inducible
molecular chaperones belonging to the heat shock protein family. The GRPs primarily reside …