Stimulatory effect of gangliosides on phagocytosis, phagosome–lysosome fusion, and intracellular signal transduction system by human polymorphonuclear …

S Yamaguchi, Y Miyazaki, S Oka, I Yano - Glycoconjugate journal, 1997 - Springer
Gangliosides are known to be differentiation-inducing molecules in mammalian stem cells.
We studied the interaction between the molecular structure of glycosphingolipids (GSLs) …

[HTML][HTML] Ganglioside GD1b suppresses immunoglobulin production by human peripheral blood mononuclear cells

N Kanda, K Tamaki - Experimental hematology, 1999 - Elsevier
Gangliosides are sialic acid-containing glycolipids, that have various immunomodulatory
effects. We previously reported that various gangliosides in vitro either inhibited or …

Gangliosides GD1a and GM3 induce interleukin-10 production by human T cells

N Kanda - Biochemical and biophysical research communications, 1999 - Elsevier
Gangliosides are sialic acid-containing glycosphingolipids and exhibit various physiologic
functions. Gangliosides GD1a and GM3 strongly induced interleukin-10 (IL-10) protein …

Analysis of phenotypic and functional changes during ganglioside-induced inhibition of human T cell proliferation

C Pique, Y Mahé, C Scamps, C Tétaud, T Tursz… - Molecular …, 1991 - Elsevier
Glycosphingolipids added to the cell culture medium can be incorporated into the plasma
membrane and interfere with the growth of certain cell types. In the past years, previous …

[HTML][HTML] Modulation of ROS production in human leukocytes by ganglioside micelles

M Gavella, M Kveder, V Lipovac - Brazilian Journal of Medical and …, 2010 - SciELO Brasil
Recent studies have reported that exogenous gangliosides, the sialic acid-containing
glycosphingolipids, are able to modulate many cellular functions. We examined the effect of …

The differentiation of HL-60 cells in the synthetic medium induced by GM3 ganglioside

H Senoo, T Momoi - Bioscience Reports, 1985 - Springer
GM3 ganglioside, added exogenously to a promyelocytic leukemia cell line (HL-60 cells) in
serum-free synthetic medium, induced differentiation into macrophage-like cells …

GM1, a ganglioside that specifically enhances immunoglobulin production and proliferation in human plasma cells

H Kimata - European journal of immunology, 1994 - Wiley Online Library
The effects of gangliosides on human plasma cell responses were studied. Among the
various gangliosides tested, only GM1 enhanced immunoglobulin (Ig) production and …

Gangliosides in the immune system: Role of glycosphingolipids and glycosphingolipid-enriched lipid rafts in immunological functions

K Iwabuchi - Gangliosides: Methods and Protocols, 2018 - Springer
Although individuals are constantly exposed to infectious agents, these agents are generally
resisted by the innate and acquired immune systems. Both the innate and acquired immune …

[HTML][HTML] Human leukocytes regulate ganglioside expression in cultured micro-pig aortic endothelial cells

JH Cho, JS Kim, MU Lim, HK Min… - Laboratory Animal …, 2012 - synapse.koreamed.org
Gangliosides are ubiquitous components of the membranes of mammalian cells that are
thought to play important roles in various cell functions such as cell-cell interaction, cell …

Gangliosides GD1b, GT1b, and GQ1b enhance IL-2 and IFN-γ production and suppress IL-4 and IL-5 production in phytohemagglutinin-stimulated human T cells

N Kanda, S Watanabe - The Journal of Immunology, 2001 - journals.aai.org
Gangliosides are sialic acid-containing glycolipids. We studied the in vitro effects of
gangliosides on Th1 and Th2 cytokine production in PHA-stimulated human T cells …