The cellular expression of adenosine A2A receptor mRNA in the adult monkey and human
striatum was examined by using single and double in situ hybridization with ribonucleotide …

It is established that dopamine (DA) controls the expression of preprodynorphin (PPDYN),
preprotachykinin A (PPT-A) and preproenkephalin (PPE) mRNAs in striatal structures. Since …

The D4 dopamine (DA) receptor has been proposed to be a target for the development of a
novel antipsychotic drug based on its pharmacological and distribution profile. There is …

Motor effects of bilateral lesions of the globus pallidus induced by quinolinic acid (30 and
60nmol in 0.5 μl) were investigated in rats. Globus pallidus lesions with 60nmol quinolinic …

It is well established that the opioid neuropeptide and dopamine systems are altered
following the use of cocaine. However very little information is available about their possible …

Neuroplasticity serves an important role for normal striatal function and in disease states.
One route to neuroplasticity involves activation of the transcription factor cyclic 3′, 5 …

The prototypical neuroleptic haloperidol and the atypical antipsychotic clozapine induce
distinctly different patterns of c-fos expression in the forebrain. While haloperidol appears to …

Striatal tissue concentrations of neurotensin, expression of neurotensin/neuromedin N
(NT/N) mRNA, and numbers of neurotensin‐immunoreactive neurons are increased by d …

One view of the efferent circuitry of the basal ganglia holds that dopamine D1 and D2
receptors are segregated to striatonigral and striatopallidal neurons, respectively. The …

In vivo microdialysis was used to study the effect of the non-selective muscarinic antagonist,
trihexyphenidyl, on the decarboxylation of levodopa (l-dopa) in the striatum of hemi …