Several novel but similar heavy metal ion transporters, Zrt1, Zrt2, Zip1-4 and Irt1, have
recently been characterized. Zrt1, Zrt2 and Zip1-4 are probably zinc transporters in …

The last ten years have witnessed major advances in our understanding of zinc transporters
and their regulation in eukaryotic organisms. Two families of transporters, the ZIP (Zrt-, I rt …

Plants require metals for essential functions ranging from respiration to photosynthesis.
These metals also contribute to the nutritional value of plants for both humans and livestock …

The Escherichia coli zupT (formerly ygiE) gene encodes a cytoplasmic membrane protein
(ZupT) related to members of the eukaryotic ZIP family of divalent metal ion transporters …

The yeast Saccharomyces cerevisiae has two separate systems for zinc uptake. One system
has high affinity for substrate and is induced in zinc-deficient cells. The second system has …

Zinc is an essential metal for all eukaryotes, and cells have evolved a complex system of
proteins to maintain the precise balance of zinc uptake, intracellular storage, and efflux. In …

Metal ion transporters of the Zrt‐and Irt‐like protein (ZIP, or SLC39A) family transport zinc,
iron, manganese and/or cadmium across cellular membranes and into the cytosol. The 14 …

The molecular basis for the transport of manganese across membranes in plant cells is
poorly understood. We have found that IRT1, an Arabidopsis thaliana metal ion transporter …

ZIP transporters (ZRT, IRT‐like proteins) are involved in the transport of iron (Fe), zinc (Zn)
and other divalent metal cations. The expression of IRT3, a ZIP transporter, is higher in the …

Iron uptake from the soil is a tightly controlled process in plant roots, involving specialized
transporters. One such transporter, IRT1, was identified in Arabidopsis thaliana and shown …