Background and purpose: In order to investigate the feasibility, toxicity and antitumor efficacy
of hyperfractionated radiation therapy, 37 adult patients with incompletely resected …

PURPOSE: To provide a 10-year update of hyperfractionated radiation therapy (Hfx RT) in
adults with incompletely resected supratentorial low-grade glioma. METHODS AND …

Results Median survival was 13.8 months and median progression-free survival was 7.4
months. The absolute Kaplan-Meier survival rate was 16% at 2 years and 4% at 5 years …

Sixty-four adult patients with malignant glioma entered into a Phase II study on the use of
accelerated hyperfractionated radiation therapy. Histology included anaplastic astrocytoma …

Abstract Between 1988 and 1993, 71 patients with glioblastoma or anaplastic astrocytoma
were treated either with accelerated hyperfractionation radiotherapy (1.5 Gy twice daily to a …

High‐grade gliomas (HGGs; WHO grades III and IV) are invariably lethal brain tumors. Low‐
dose hyper‐radiosensitivity (HRS) of HGG is a well‐established phenomenon in vitro …

In this prospective study, we investigated the effects of hypofractionated radiotherapy for
patients with high-grade gliomas. About 31 patients with glioblastoma multiforme or …

Ultrafractionation of radiation therapy is a novel regimen consisting of irradiating tumors
several times daily, delivering low doses (< 0.75 Gy) at which hyperradiosensitivity occurs …

Purpose: To see whether increasing the dose of hyperfractionated radiation therapy from 72
to 78 Gy would increase survival time in patients with gliomas, particularly those with brain …

A prospective randomized study of 108 patients with cerebral malignant gliomas was carried
out at the Department of Radiation Oncology of Maria Sklodowska-Curie Memorial Center in …