Evolutionary biologists have long sought a way to determine whether a phenotypic
difference between two taxa was caused by natural selection or random genetic drift. Here I …

Until recently, it was impracticable to identify the genes that are responsible for variation in
continuous traits, or to directly observe the effects of their different alleles. Now, the …

Quantitative genetics is at or is fast approaching its centennial. In this perspective I consider
five current issues pertinent to the application of quantitative genetics to evolutionary theory …

The past decade has seen a proliferation of studies that employ quantitative trait locus (QTL)
approaches to diagnose the genetic basis of trait evolution. Advances in molecular …

Selection is widely accepted as the principal force shaping phenotypic variation within
populations. Its importance in speciation and macroevolution has been questioned …

The comparison between neutral genetic differentiation (FST) and quantitative genetic
differentiation (QST) is commonly used to test for signatures of selection in population …

The comparison of the degree of differentiation in neutral marker loci and genes coding
quantitative traits with standardized and equivalent measures of genetic differentiation (F ST …

Comparisons between putatively neutral genetic differentiation amongst populations, FST,
and quantitative genetic variation, QST, are increasingly being used to test for natural …

DNA markers allow us to study quantitative trait loci (QTL)—the genes that control
adaptation and quantitative variation. Experiments can map the genes responsible for …

While it is well understood that the pace of evolution depends on the interplay between
natural selection, random genetic drift, mutation, and gene flow, it is not always easy to …