Microsatellite instability and mutation of DNA mismatch repair genes in gliomas
SY Leung, TL Chan, LP Chung, ASY Chan… - The American journal of …, 1998 - Elsevier
Microsatellite instability (MSI) has been identified in various human cancers, particularly
those associated with the hereditary nonpolyposis colorectal cancer syndrome. Although …
those associated with the hereditary nonpolyposis colorectal cancer syndrome. Although …
Reduced expression of mismatch repair genes measured by multiplex reverse transcription-polymerase chain reaction in human gliomas
Microsatellite instability (MIN) is frequently observed in hereditary nonpolyposis colon
cancer and in other sporadic cancers including gliomas. Abnormalities in at least one of five …
cancer and in other sporadic cancers including gliomas. Abnormalities in at least one of five …
Microsatellite instability in pediatric and adult high‐grade gliomas
A Eckert, M Kloor, A Giersch, R Ahmadi… - Brain …, 2007 - Wiley Online Library
About 15% of sporadic gastrointestinal and endometrial tumors show the microsatellite
instability (MSI) phenotype because of loss of DNA mismatch repair (MMR) function. The …
instability (MSI) phenotype because of loss of DNA mismatch repair (MMR) function. The …
Microsatellite instability occurs in distinct subtypes of pediatric but not adult central nervous system tumors
M Alonso, R Hamelin, M Kim, K Porwancher, T Sung… - Cancer research, 2001 - AACR
Length alterations in microsatellite repeats, termed microsatellite instability (MSI), are found
in 10–15% of sporadic colon, endometrial, and gastric cancers harboring defects in DNA …
in 10–15% of sporadic colon, endometrial, and gastric cancers harboring defects in DNA …
Microsatellite Instability in Colorectal Cancer: Different Mutator Phenotypes and the Principal Involvement of hMLH1
SN Thibodeau, AJ French, JM Cunningham, D Tester… - Cancer research, 1998 - AACR
Recent studies have demonstrated the presence of microsatellite instability (MSI) in tumors
from patients with hereditary nonpolyposis colorectal cancer and in a large number of …
from patients with hereditary nonpolyposis colorectal cancer and in a large number of …
Chromosomal instability and p53 inactivation are required for genesis of glioblastoma but not for colorectal cancer in patients with germline mismatch repair gene …
SY Leung, ST Yuen, TL Chan, ASY Chan, JWC Ho… - Oncogene, 2000 - nature.com
We have previously reported high-frequency microsatellite instability (MSI-H) and germ-line
mismatch repair gene mutation in patients with unusually young onset of high-grade glioma …
mismatch repair gene mutation in patients with unusually young onset of high-grade glioma …
Microsatellite instability and the role of hMSH2 in sporadic colorectalcancer.
VJ Bubb, LJ Curtis, C Cunningham, MG Dunlop… - Oncogene, 1996 - europepmc.org
Microsatellite instability (MSI) occurs in most tumours from patients with hereditary non-
polyposis colorectal cancer (HNPCC) and in around 17% of sporadic colorectal cancers …
polyposis colorectal cancer (HNPCC) and in around 17% of sporadic colorectal cancers …
Causes of microsatellite instability in colorectal tumors: implications for hereditary non-polyposis colorectal cancer screening
U Potočnik, D Glavač, R Golouh… - Cancer genetics and …, 2001 - Elsevier
Microsatellite instability (MSI) analysis was performed using a “reference panel” of
microsatellite markers in 345 unselected primary colorectal cancers (CRC). Thirty-five (10%) …
microsatellite markers in 345 unselected primary colorectal cancers (CRC). Thirty-five (10%) …
Microsatellite instability in gastrointestinal tract cancers: a brief update
S Oda, Y Zhao, Y Maehara - Surgery today, 2005 - Springer
Microsatellite instability (MSI) was initially reported in colorectal cancer and, particularly, in
hereditary nonpolyposis colorectal cancer (HNPCC). Since mutations in the genes …
hereditary nonpolyposis colorectal cancer (HNPCC). Since mutations in the genes …
Microsatellite instability in malignant melanoma
VR Talwalkar, M Scheiner, LK Hedges… - Cancer genetics and …, 1998 - Elsevier
Defective mismatch repair has been detected in human colorectal and endometrial
carcinomas which exhibit microsatellite instability (MIN). The purpose of this study was to …
carcinomas which exhibit microsatellite instability (MIN). The purpose of this study was to …
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