During receptor-mediated endocytosis, ligands bind to their receptors and are incorporated
into clathrin coated vesicles. These vesicles bud from the plasma membrane, shed their …

Receptor-mediated endocytosis and recycling are inhibited in mitotic mammalian cells, and
previous studies have shown that inhibition of endocytic vesicle fusion in vitro occurs via …

It is now clear that complexes of cdc2 kinase with “mitotic” cyclins regulate the transition
between the G2 phase of the cell cycle and mitosis and that membrane traffic in mammalian …

MEMBRANE transport between the endoplasmic reticulum and the plasma membrane,
which involves the budding and fusion of carrier vesicles, is inhibited during mitosis in …

A long-standing paradigm in cell biology is the shutdown of endocytosis during mitosis.
There is consensus that transferrin uptake is inhibited after entry into prophase and that it …

Recent studies have implicated the cell cycle kinase cdc2 and cyclin A in the inhibition of the
fusion of endocytic vesiclesin vitroduring mitosis. However, the presence of cyclins or their …

We have isolated and characterized cDNA encoding a human 58-kDa protein kinase that is
homologous to the cell division control (CDC) protein kinases. This protein kinase also …

The hexameric ATPase p97/yeast Cdc48p has been implicated in anumber of cellular
events that are regulated during mitosis, including homotypic membrane fusion, spindle pole …

Okadaic acid and microcystin-LR, both potent inhibitors of protein phosphatases (PP),
blocked vesicle fusion in a cell-free system. The effect of okadaic acid was reversed by the …

Recent work has underscored the importance of membrane trafficking events during
cytokinesis. For example, targeted membrane secretion occurs at the cleavage furrow in …