Dynamic interactions between splicing snRNPs, coiled bodies and nucleoli revealed using snRNP protein fusions to the green fluorescent protein
The U1, U2, U4/U6, and U5 small nuclear ribonucleoproteins (snRNPs) are subunits of
splicing complexes that remove introns from mRNA precursors. snRNPs show a complex …
splicing complexes that remove introns from mRNA precursors. snRNPs show a complex …
High intranuclear mobility and dynamic clustering of the splicing factor U1 snRNP observed by single particle tracking
T Kues, A Dickmanns, R Lührmann… - Proceedings of the …, 2001 - National Acad Sciences
Uridine-rich small nuclear ribonucleoproteins (U snRNPs) are components of the splicing
machinery that removes introns from precursor mRNA. Like other splicing factors, U snRNPs …
machinery that removes introns from precursor mRNA. Like other splicing factors, U snRNPs …
[HTML][HTML] Newly assembled snRNPs associate with coiled bodies before speckles, suggesting a nuclear snRNP maturation pathway
JE Sleeman, AI Lamond - Current Biology, 1999 - cell.com
Background: Small nuclear ribonucleoproteins (snRNPs), which are essential components
of the mRNA splicing machinery, comprise small nuclear RNAs, each complexed with a set …
of the mRNA splicing machinery, comprise small nuclear RNAs, each complexed with a set …
Differential interaction of splicing snRNPs with coiled bodies and interchromatin granules during mitosis and assembly of daughter cell nuclei.
JA Ferreira, M Carmo-Fonseca, AI Lamond - The Journal of cell biology, 1994 - rupress.org
In the interphase nucleus of mammalian cells the U1, U2, U4/U6, and U5 small nuclear
ribonucleoproteins (snRNPs), which are subunits of spliceosomes, associate with specific …
ribonucleoproteins (snRNPs), which are subunits of spliceosomes, associate with specific …
Inhibition of protein dephosphorylation results in the accumulation of splicing snRNPs and coiled bodies within the nucleolus
Coiled bodies are conserved subnuclear organelles that contain splicing snRNPs, a subset
of nucleolar antigens, and the autoantigen p80 coilin. Most nuclei contain one to five …
of nucleolar antigens, and the autoantigen p80 coilin. Most nuclei contain one to five …
[引用][C] Localisation of splicing snRNPs in mammalian cells
AI Lamond, M Carmo-Fonseca - Molecular biology reports, 1993 - Springer
The U1, U2, U4/U6 and U5 small nuclear ribonucleoprotein particles (snRNPs) are subunits
of spliceosomes. They are comprised of one or more small nuclear RNAs (snRNAs) and a …
of spliceosomes. They are comprised of one or more small nuclear RNAs (snRNAs) and a …
[HTML][HTML] The differential interaction of snRNPs with pre-mRNA reveals splicing kinetics in living cells
M Huranová, I Ivani, A Benda, I Poser… - The Journal of cell …, 2010 - ncbi.nlm.nih.gov
Precursor messenger RNA (pre-mRNA) splicing is catalyzed by the spliceosome, a large
ribonucleoprotein (RNP) complex composed of five small nuclear RNP particles (snRNPs) …
ribonucleoprotein (RNP) complex composed of five small nuclear RNP particles (snRNPs) …
Interactions between small nuclear ribonucleoprotein particles in formation of spliceosomes
MM Konarska, PA Sharp - Cell, 1987 - cell.com
Electrophoretic separation of ribonucleoprotein particles in a nondenaturing gel was used to
analyze the splicing of mRNA precursors. Early in the reaction, a complex formed consisting …
analyze the splicing of mRNA precursors. Early in the reaction, a complex formed consisting …
[HTML][HTML] Combined biochemical and electron microscopic analyses reveal the architecture of the mammalian U2 snRNP
A Krämer, P Grüter, K Gröning… - The Journal of cell …, 1999 - ncbi.nlm.nih.gov
The 17S U2 small nuclear ribonucleoprotein particle (snRNP) represents the active form of
U2 snRNP that binds to the pre-mRNA during spliceosome assembly. This particle forms by …
U2 snRNP that binds to the pre-mRNA during spliceosome assembly. This particle forms by …
Targeted snRNP depletion reveals an additional role for mammalian U1 snRNP in spliceosome assembly
SML Barabino, BJ Blencowe, U Ryder, BS Sproat… - Cell, 1990 - cell.com
HeLa cell nuclear splicing extracts have been prepared that are specifically and efficiently
depleted of Ul, U2, or U4/U6 snRNPs by antlsense affinity chromatography using …
depleted of Ul, U2, or U4/U6 snRNPs by antlsense affinity chromatography using …
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