Although memory deficits are associated with major depressive disorder, few studies have
identified which patient characteristics predict impairment. Because recurrent depression …

Many symptoms of PTSD represent conditioned responses to stimuli associated with a
traumatic experiences. In this review, we propose that the anterior cingulate—a brain region …

Background. The hippocampus, amygdala and related functional circuits have been
implicated in the regulation of emotional expression and memory processes, which are …

Background Pindolol has been reported to hasten the antidepressant action of selective
serotonin reuptake inhibitors in open-label and placebo-controlled trials. Pilot studies also …

Investigations of the biochemical actions of lithium have identified many individual reactions
that are affected, especially within cellular signaling systems, but the actions of lithium at …

Major depression affects about one in five patients in the weeks after an acute myocardial
infarction and is associated with an increased risk of cardiac morbidity and mortality …

Glucocorticoid hormones are important for coping with stress but may have deleterious
effects on mood and memory during prolonged excessive secretion. A key abnormality …

OBJECTIVE: Previous studies reported that depressed subjects had more white matter
hyperintensities on magnetic resonance imaging scans than control subjects, but the …

The risk of recurrence in affective disorder is influenced by the number of prior episodes and
by a person's tendency toward recurrence. Newly developed frailty models were used to …

Transcranial magnetic stimulation (TMS) has become a promising treatment of affective
disorders in humans, yet the neuronal basis of its long-lasting effects in the brain is still …