What has been learned from measuring health-related quality of life in clinical oncology

D Osoba - European journal of cancer, 1999 - Elsevier
The measurement of health-related quality of life (HRQL) in oncology clinical trials has come
of age. Most cooperative clinical trials groups as well as individual institutions have either …

Lessons learned from measuring health-related quality of life in oncology.

D Osoba - Journal of clinical oncology, 1994 - ascopubs.org
PURPOSE Measurement of health-related quality of life (HQL) is becoming more common in
oncology, particularly in clinical trials. The purpose of this report is to review our progress …

Health related quality of life outcomes in cancer clinical trials

A Bottomley, H Flechtner, F Efficace… - European Journal of …, 2005 - Elsevier
Over the last decade, health related quality of life (HRQOL) investigations have become an
increasingly important part of many cancer clinical trial research programs. This paper …

Other paradigms: health-related quality of life as a measure in cancer treatment: its importance and relevance

PC Trask, MA Hsu, R McQuellon - The Cancer Journal, 2009 - journals.lww.com
During the past 2 decades, there have been advances in the definition, measurement, and
application in clinical trials and practice of health-related quality of life (HRQOL). In addition …

Quality of life instruments in oncology

G Velikova, D Stark, P Selby - European Journal of Cancer, 1999 - Elsevier
The objective of this article is to aid clinicians in understanding the current state of the
development and application of quality of life (QOL) instruments as outcome measures in …

Analysis and interpretation of health-related quality-of-life data from clinical trials: basic approach of The National Cancer Institute of Canada Clinical Trials Group

D Osoba, A Bezjak, M Brundage, B Zee, D Tu… - European journal of …, 2005 - Elsevier
Clinicians are being confronted with increasing amounts of health-related quality of life
(HRQOL) data. Thus, there is a need for a greater understanding of the analysis and …

International perspective on health-related quality-of-life research in cancer clinical trials: the European Organisation for Research and Treatment of Cancer …

A Bottomley, NK Aaronson - Journal of Clinical Oncology, 2007 - ascopubs.org
Over recent decades, health-related quality of life (HRQOL) research has been increasingly
integrated into cancer clinical trials. The purpose of this review is to examine the overall …

Reporting of health-related quality of life (HRQOL) data in oncology trials: a comparison of the European Organization for Research and Treatment of Cancer Quality …

AB Smith, K Cocks, D Parry, M Taylor - Quality of life Research, 2014 - Springer
Purpose The inclusion of patient-reported outcome (PRO) instruments to record patient
health-related quality of life (HRQOL) data has virtually become the norm in oncology …

Quality-of-life assessment in oncology

MAG Sprangers - Acta Oncologica, 2002 - Taylor & Francis
In this article important areas of health-related quality of life (H RQL) research and major
achievements are described, illustrated by studies conducted with cancer patients. Some of …

Measurement of quality of life in clinical trials

S Kaasa - Oncology, 1992 - karger.com
Abstract Information on patients' quality of life (QOL) will give a more comprehensive
evaluation of the treatment outcome than only measures of tumour response and survival …