Vascular endothelial (VE)-cadherin: only an intercellular glue?

E Dejana, G Bazzoni, MG Lampugnani - Experimental cell research, 1999 - Elsevier
Data collected during the past years indicate that AJ-and more specifically VE-cadherin play
an important role in endothelial cell biology. VE-cadherin may transfer information …

The role of VE-cadherin in vascular morphogenesis and permeability control

E Dejana, D Vestweber - Progress in molecular biology and translational …, 2013 - Elsevier
VE-cadherin is an endothelial-specific cadherin that is essential for the formation and
regulation of endothelial cell junctions. The adhesive function and expression levels of VE …

Vascular endothelial–cadherin is an important determinant of microvascular integrity in vivo

M Corada, M Mariotti, G Thurston… - Proceedings of the …, 1999 - National Acad Sciences
In the present paper, we characterize an antibody, mAb BV13, directed to mouse vascular
endothelial (VE)-cadherin, a major adhesive protein of interendothelial adherens junctions …

Differential localization of VE-and N-cadherins in human endothelial cells: VE-cadherin competes with N-cadherin for junctional localization

P Navarro, L Ruco, E Dejana - The Journal of cell biology, 1998 - rupress.org
The two major cadherins of endothelial cells are neural (N)-cadherin and vascular
endothelial (VE)-cadherin. Despite similar level of protein expression only VE-cadherin is …

VE-cadherin and endothelial adherens junctions: active guardians of vascular integrity

M Giannotta, M Trani, E Dejana - Developmental cell, 2013 - cell.com
VE-cadherin is a component of endothelial cell-to-cell adherens junctions, and it has a key
role in the maintenance of vascular integrity. During embryo development, VE-cadherin is …

N-cadherin acts upstream of VE-cadherin in controlling vascular morphogenesis

Y Luo, GL Radice - The Journal of cell biology, 2005 - rupress.org
Endothelial cells express two classic cadherins, VE-cadherin and N-cadherin. The
importance of VE-cadherin in vascular development is well known; however, the function of …

VE-cadherin: the major endothelial adhesion molecule controlling cellular junctions and blood vessel formation

D Vestweber - Arteriosclerosis, thrombosis, and vascular biology, 2008 - Am Heart Assoc
Vascular endothelial (VE)-cadherin is a strictly endothelial specific adhesion molecule
located at junctions between endothelial cells. In analogy of the role of E-cadherin as major …

Vascular endothelial cadherin (VE‐cadherin): Cloning and role in endothelial cell‐cell adhesion

J Ali, F Liao, E Martens, WA Muller - Microcirculation, 1997 - Wiley Online Library
Objective: To identify proteins responsible for intercellular junction integrity in human
umbilical vein endothelial cells (HUVEC), we produced a monoclonal antibody that …

Mechanisms of VE-cadherin processing and degradation in microvascular endothelial cells

K Xiao, DF Allison, MD Kottke, S Summers… - Journal of Biological …, 2003 - ASBMB
VE-cadherin is an endothelial-specific cadherin that plays important roles in vascular
morphogenesis and growth control. To investigate the mechanisms by which endothelial …

VE-cadherin: at the front, center, and sides of endothelial cell organization and function

ES Harris, WJ Nelson - Current opinion in cell biology, 2010 - Elsevier
Endothelial cells form cell–cell adhesive structures, called adherens and tight junctions,
which maintain tissue integrity, but must be dynamic for leukocyte transmigration during the …