Effect of Trichloroethylene and Its Metabolites, Dichloroacetic Acid and Trichloroacetic Acid, on the Methylation and Expression of c-Jun and c-Myc Protooncogenes …
L Tao, S Yang, MI Xie, PM Kramer… - Toxicological …, 2000 - academic.oup.com
Abstract Trichloroethylene (TCE), dichloroacetic acid (DCA), and trichloroacetic acid (TCA)
are environmental contaminants that are carcinogenic in mouse liver. 5-Methylcytosine (5 …
are environmental contaminants that are carcinogenic in mouse liver. 5-Methylcytosine (5 …
Effect of trichloroethylene on DNA methylation and expression of early‐intermediate protooncogenes in the liver of B6C3F1 mice
L Tao, R Ge, M Xie, PM Kramer… - Journal of Biochemical …, 1999 - Wiley Online Library
Trichloroethylene (TCE) is a multimedia environmental pollution that is carcinogenic in
mouse liver. The ability of TCE to modulate DNA methylation and the expression of …
mouse liver. The ability of TCE to modulate DNA methylation and the expression of …
Effect of chloroform on dichloroacetic acid and trichloroacetic acid-induced hypomethylation and expression of the c- myc gene and on their promotion …
MA Pereira, PM Kramer, PB Conran, L Tao - Carcinogenesis, 2001 - academic.oup.com
Chloroform, dichloroacetic acid (DCA) and trichloroacetic acid (TCA) are mouse liver
carcinogens that are chlorine disinfection by-products found in drinking water. The effect of …
carcinogens that are chlorine disinfection by-products found in drinking water. The effect of …
Hypomethylation and overexpression of c-jun and c-myc protooncogenes and increased DNA methyltransferase activity in dichloroacetic and trichloroacetic acid …
L Tao, S Yang, M Xie, PM Kramer, MA Pereira - Cancer letters, 2000 - Elsevier
Dichloroacetic acid (DCA) and trichloroacetic acid (TCA) are mouse liver carcinogens.
Methylation of the c-jun and c-myc genes, expression of both genes and DNA …
Methylation of the c-jun and c-myc genes, expression of both genes and DNA …
Effect of dichloroacetic acid and trichloroacetic acid on DNA methylation in liver and tumors of female B6C3F1 mice
L Tao, PM Kramer, R Ge, MA Pereira - Toxicological sciences, 1998 - Elsevier
Dichloroacetic acid (DCA) and trichloroacetic acid (TCA) are found in drinking water and are
metabolites of trichloroethylene. They are carcinogenic and promote liver tumors in B6C3F1 …
metabolites of trichloroethylene. They are carcinogenic and promote liver tumors in B6C3F1 …
Hypomethylation of DNA and the insulin-like growth factor-II gene in dichloroacetic and trichloroacetic acid-promoted mouse liver tumors
L Tao, Y Li, PM Kramer, W Wang, MA Pereira - Toxicology, 2004 - Elsevier
Dichloroacetic acid (DCA) and trichloroacetic acid (TCA) are mouse liver carcinogens. DNA
hypomethylation is a common molecular event in cancer that is induced by DCA and TCA …
hypomethylation is a common molecular event in cancer that is induced by DCA and TCA …
The effect of dichloroacetic acid and trichloroacetic acid on DNA methylation and cell proliferation in B6C3F1 mice
R Ge, S Yang, PM Kramer, L Tao… - Journal of Biochemical …, 2001 - Wiley Online Library
The chlorine disinfection by‐products, dichloroacetic acid (DCA) and trichloroacetic acid
(TCA), are carcinogenic in mouse liver. We have previously reported that DCA and TCA …
(TCA), are carcinogenic in mouse liver. We have previously reported that DCA and TCA …
Effect of trihalomethanes on cell proliferation and DNA methylation in female B6C3F1 mouse liver
JC Coffin, R Ge, S Yang, PM Kramer, L Tao… - Toxicological …, 2000 - academic.oup.com
Abstract Trihalomethanes (chloroform, bromodichloromethane, chlorodibromomethane, and
bromoform) are regulated organic contaminants in chlorinated drinking water. In female …
bromoform) are regulated organic contaminants in chlorinated drinking water. In female …
Prevention by methionine of dichloroacetic acid–induced liver cancer and DNA hypomethylation in mice
MA Pereira, W Wang, PM Kramer… - Toxicological sciences, 2004 - academic.oup.com
Dichloroacetic acid (DCA) is a liver carcinogen that induces DNA hypomethylation in mouse
liver. To test the involvement of DNA hypomethylation in the carcinogenic activity of DCA, we …
liver. To test the involvement of DNA hypomethylation in the carcinogenic activity of DCA, we …
Methyl groups in carcinogenesis: effects on DNA methylation and gene expression
E Wainfan, LA Poirier - Cancer research, 1992 - AACR
Abstract Lipotrope-deficient (methyl-deficient) diets cause fatty livers and increased liver-cell
turnover and promote carcinogenesis in rodents. In rats prolonged intake of methyl-deficient …
turnover and promote carcinogenesis in rodents. In rats prolonged intake of methyl-deficient …
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