Plasma free fatty acids (FFA) might mediate the insulin resistance and impaired glucose
tolerance associated with central obesity. Central adipocytes are resistant to insulin …

Plasma free fatty acids (FFA) play important physiological roles in skeletal muscle, heart,
liver and pancreas. However, chronically elevated plasma FFA appear to have …

Investigates the role of free fatty acids (FFA) in type 2 diabetes. Effect of FFA on skeletal
muscle, the liver, and the pancreas; FFA interactions in the pancreas; Regional differences …

Objective To present evidence that free fatty acids (FFA) are an important link between
obesity and insulin resistance. Methods The role of FFA in peripheral insulin resistance …

Most obese individuals have elevated plasma levels of free fatty acids (FFA) which are
known to cause peripheral (muscle) insulin resistance. They do this by inhibiting insulin …

Evidence is presented that shows that free fatty acids (FFA) are one important link between
obesity, insulin resistance, and type 2 diabetes. Plasma FFA levels are elevated in most …

Evidence is reviewed that free fatty acids (FFAs) are one important link between obesity and
insulin resistance and NIDDM. First, plasma FFA levels are elevated in most obese subjects …

Free fatty acids (FFAs) circulate round the body and represent important nutrients and the
key oxidative fuel for the heart and resting skeletal muscle. In addition, FFAs are thought to …

The increase in free fatty acid flux resulting from increased lipolysis secondary to adipose-
tissue insulin resistance induces or aggravates insulin resistance in liver and muscle …

Acute increases in plasma levels of long-chain fatty acids raise plasma insulin levels by
stimulating insulin secretion or by decreasing insulin clearance. In normal subjects, longterm …