Bispecific heteroantibodies with dual effector functions
MW Fanger, PM Guyre, ED Ball - US Patent 6,071,517, 2000 - Google Patents
Bispecific molecules which react both with the high-affinity Fcγ receptor of human effector
cells and with a target cell surface antigen are disclosed. Binding of the molecules to the Fc …
cells and with a target cell surface antigen are disclosed. Binding of the molecules to the Fc …
Methods for use of monoclonal antibodies specific for the high affinity Fc receptor for immunoglobulin G
MW Fanger, PM Guyre, CL Anderson - US Patent 6,096,311, 2000 - Google Patents
Monoclonal antibodies which react specifically to Fc receptor of human effector cells are
disclosed. Binding of the antibodies to the receptor is not blocked by human immunoglobulin …
disclosed. Binding of the antibodies to the receptor is not blocked by human immunoglobulin …
Anti-Fc-gamma receptor antibodies, bispecific variants and uses therefor
AC Chan, RL Shields, L Wu - US Patent 7,662,926, 2010 - Google Patents
C07K16/283—Immunoglobulins [IGs], eg monoclonal or polyclonal antibodies against
material from animals or humans against receptors, cell surface antigens or cell surface …
material from animals or humans against receptors, cell surface antigens or cell surface …
Bifunctional and heteroantibodies specific for the high affinity Fc receptor for immunoglobulin G on human mononuclear phagocytes
MW Fanger, PM Guyre, CL Anderson - US Patent 5,635,600, 1997 - Google Patents
Monoclonal antibodies which react speci? cally to Fe recep tor of human eifector cells IgG
are disclosed. Binding of the antibodies to the receptor is not blocked by human immu …
are disclosed. Binding of the antibodies to the receptor is not blocked by human immu …
Bispecific molecules for use in inducing antibody dependent effector cell-mediated cytotoxicity
ED Ball, MW Fanger - US Patent 5,833,985, 1998 - Google Patents
In one aspect, the invention relates to a bispecific mol ecule comprising a target cell Specific
ligand and an antibody or functional antibody fragment Specific for an effector cell. In a …
ligand and an antibody or functional antibody fragment Specific for an effector cell. In a …
Antibodies with altered effector functions
GP Winter, AR Duncan, DR Burton - US Patent 5,624,821, 1997 - Google Patents
US5624821A - Antibodies with altered effector functions - Google Patents US5624821A -
Antibodies with altered effector functions - Google Patents Antibodies with altered effector …
Antibodies with altered effector functions - Google Patents Antibodies with altered effector …
Therapeutic compounds comprised of anti-Fc receptor antibodies
YM Deo, J Goldstein, R Graziano… - US Patent …, 2002 - Google Patents
US6410690B1 - Therapeutic compounds comprised of anti-Fc receptor antibodies - Google
Patents US6410690B1 - Therapeutic compounds comprised of anti-Fc receptor antibodies …
Patents US6410690B1 - Therapeutic compounds comprised of anti-Fc receptor antibodies …
Therapeutic compounds comprised of anti-Fc receptor antibodies
YM Deo, J Goldstein, R Graziano… - US Patent …, 1998 - Google Patents
US5837243A - Therapeutic compounds comprised of anti-Fc receptor antibodies - Google
Patents US5837243A - Therapeutic compounds comprised of anti-Fc receptor antibodies …
Patents US5837243A - Therapeutic compounds comprised of anti-Fc receptor antibodies …
Targeted immunostimulation with bispecific reagents
JL Romet-Lemonne, MW Fanger, PM Guyre… - US Patent …, 2001 - Google Patents
This invention pertains to a binding agent which binds a Surface receptor of an antigen-
presenting cell in Some instances without being blocked Substantially by the natural ligand …
presenting cell in Some instances without being blocked Substantially by the natural ligand …
Preparation of human, humanized or chimaeric antibodies or polypeptides having different binding profiles to Fcgamma receptors
D Bourel, C De Romeuf, S Siberil, WH Fridman… - US Patent …, 2010 - Google Patents
The present invention relates to a method for the production and the selection of human or
chimæric or humanized antibodies or molecules that comprise the Fc region of human IgG …
chimæric or humanized antibodies or molecules that comprise the Fc region of human IgG …