Methods of stimulating or enhancing the immune system with anti-CD3 antibodies

JA Bluestone - US Patent 6,113,901, 2000 - Google Patents
Disclosed are immunopotentiating agents, and vaccines thereof, which enhance and/or
otherwise modify immune responses, and methods for their preparation and use in vivo …

Methods of stimulating the immune system with anti-CD3 antibodies

JA Bluestone - US Patent 6,406,696, 2002 - Google Patents
Disclosed are immunopotentiating agents, and vaccines thereof, which enhance and/or
otherwise modify immune responses, and method for their preparation and use in vivo …

Methods of promoting immunopotentiation and preparing antibodies with anti-CD3 antibodies

JA Bluestone - US Patent 6,143,297, 2000 - Google Patents
Disclosed are immunopotentiating agents, and vaccines thereof, which enhance and/or
otherwise modify immune responses, and method for their preparation and use in vivo …

Anti-CD4 antibodies

M Frewin, H Waldmann, S Gorman, G Hale… - US Patent …, 2009 - Google Patents
This is a continuation-in-part application of US applica tion Ser. No. 10/171452, filed Jun. 13,
2002 now abandoned, which claims priority to GB application No. 0114517.6, filed Jun. 14 …

Synthetic antigens for CD1-restricted immune responses

S Porcelli, D Moody - US Patent App. 10/438,383, 2003 - Google Patents
Synthetic antigens which comprise hydrophobic and hydrophilic components are provided
for inducing CD1-restricted T cell responses in mammals. Further provided are methods for …

Non-depleting anti-CD4 monoclonal antibodies and tolerance induction

SP Cobbold, H Waldmann - US Patent 6,056,956, 2000 - Google Patents
Tolerance to an antigen is induced in a Subject by adminis tering a non-depleting CD4
monoclonal antibody and a non-depleting CD8 monoclonal antibody. Tolerance to the …

Methods and compositions for immunomodulation

I Van Rhijn, DC Young, DB Moody - US Patent 7,795,242, 2010 - Google Patents
US7795242B2 - Methods and compositions for immunomodulation - Google Patents
US7795242B2 - Methods and compositions for immunomodulation - Google Patents Methods …

Immunostimulatory compositions and methods

H Shirwan, KG Elpek, ES Yolcu - US Patent 7,598,345, 2009 - Google Patents
The invention provides conjugates comprising an immune co-stimulatory polypeptide and
an antigen or infectious agent. The conjugates are useful for generating or enhancing an …

Fully human anti-CD3 monoclonal antibodies

T Delovitch - US Patent App. 11/502,870, 2006 - Google Patents
Non-toxic anti-CD3 antibody is useful for the treatment, prevention, and reversal of human
autoimmune disease. Anti-CD3 antibody is generated by immunizing xenogenic mice …

Immunostimulatory compositions and methods

H Shirwan, KG Elpek, ES Yolcu - US Patent 8,017,582, 2011 - Google Patents
The invention provides conjugates comprising an immune co-stimulatory polypeptide and
an antigen or infectious agent. The conjugates are useful for generating or enhancing an …