63 Continuation of application No. 08/028,527, Mar. 9, 1993, abandoned, which is a
continuation of application No. 07/880,307, May 5, 1992, abandoned, which is a continua …

Continuation of application No. 08/451,848, filed on May 26, 1995, now Pat. No. 5,714,147,
which is a continuation of application No. 08/185,670, filed on Jan. 21, 1994, now Pat. No …

Chimeric molecules having a ligand component linked to an immunoglobulin constant
region component are provided for various diagnostic, therapeutic and other uses. These …

Several forms of immunoregulatory Substances are derived from monoclonal antibodies
(MAbs) that are specific for a T cell surface antigen, such as CD3, TCR, CD4, or CD8 on T …

It is, therefore, an object of the present invention to provide a means by which elements of
the immune system can be targeted against specific types of un wanted or detrimental cells …

The foregoing objects can be achieved by providing a modi? ed antibody or antibody
fragment, consisting essentially of:(l) at least one hypervariable region which speci? cally …

Johnson et al.,“Prolonged and preferential production of polymeric immunoglobulin A in
response to StreptococcuS pneumoniae capsular polysaccharides' Infection and Immu nity …

The present invention relates to a novel process for the preparation of biologically active
antibody dimers in a pharmaceutically acceptable composition. The dimers can be …

Novel conjugate of the general formula wherein A and B are the substances to be coupled
selected from the groups of haptens, proteins, polysaccharides, soluble polystyrenes, or …

This invention relates to antibody-therapeutic agent. conjugates having a therapeutic agent
covalently at tached to an antibody or antibody fragment. Also de scribed are methods for …