This book will serve as the definitive reference work on the basic physiology, biochemistry,
development, genetics, and molecular biology of Neurospora, together with a description of …

Publisher Summary This chapter describes the microbiological and genetic handling of
Neurospora crassa. It also reviews the biochemical methods of Neurospora. The simpler …

Under the title “Fifty Years Ago: The Neuro-spora Revolution,” HOROWITZ (1 99 1) has
celebrated an anniversary of the epochal 1941 paper of BEADLE and TATUM, which …

Within recent years there has been a noticeable shift in emphasis in the field of genetics
away from studies on the mechanism of gene transmission to investigations in such …

On this occasion of sharing the high honor of a Nobel award with Edward L. Tatum for our"
discovery that genes act by regulating chemical events," andwith Joshua Lederberg for his …

In the 1940s, studies with Neurospora pioneered the use of microorganisms in genetic
analysis and provided the foundations for biochemical genetics and molecular biology. What …

INEODUCTION Apologia For the would-be writer of a review article, it can besobering to ask
whether the article is needed. On posing this question to myself, I realized that a number of …

Publisher Summary The Neurospora investigations have made clear that the gene is at the
basis of the synthetic chemical activities of the cell. This chapter highlights the current status …

Materials and Methods.-Cultures: The strain col-2 (Y5331) was backcrossed twice tothe
Rockefeller wild-type strain (RL 3-8A), and the resulting colonial isolates designated as col …

We have developed a sib selection procedure for cloning Neurospora crassa nuclear genes
by complementation of mutants. This procedure takes advantage of a modified N. crassa …