A specific interferon (IFN)-stimulated response element of the distal HLA-G promoter binds IFN-regulatory factor 1 and mediates enhancement of this nonclassical …

S Lefebvre, S Berrih-Aknin, F Adrian, P Moreau… - Journal of Biological …, 2001 - ASBMB
Type I interferons display a broad range of immunomodulatory functions. Interferon β
increases gene expression at the transcriptional level through binding of factors to the …

The truncated cytoplasmic tail of HLA-G serves a quality-control function in post-ER compartments

B Park, S Lee, E Kim, S Chang, M Jin, K Ahn - Immunity, 2001 - cell.com
In contrast to the current model of MHC class I trafficking, which predicts that once a MHC
class I molecule leaves the ER, it moves to the cell surface by bulk flow, we show that HLA-G …

Expression of Epstein-Barr virus-induced gene 3, an interleukin-12 p40-related molecule, throughout human pregnancy: involvement of syncytiotrophoblasts and …

O Devergne, A Coulomb-L'Herminé, F Capel… - The American journal of …, 2001 - Elsevier
In human pregnancy, trophoblasts are the only cells of fetal origin in direct contact with the
maternal immune system: syncytiotrophoblasts are in contact with maternal blood, whereas …

Promiscuous antigen presentation by the nonclassical MHC Ib Qa-2 is enabled by a shallow, hydrophobic groove and self-stabilized peptide conformation

X He, P Tabaczewski, J Ho, I Stroynowski, KC Garcia - Structure, 2001 - cell.com
Background: Qa-2 is a nonclassical MHC Ib antigen, which has been implicated in both
innate and adaptive immune responses, as well as embryonic development. Qa-2 has an …

[HTML][HTML] Is antigen presentation the primary function of HLA-G?

P Le Bouteiller, C Solier - Microbes and infection, 2001 - Elsevier
Human histocompatibility leukocyte antigen (HLA)-G is an antigen-presenting molecule.
This review discusses the possibility that this might not be its primary function. HLA-G indeed …

[PDF][PDF] Characterization of HLA-G1,-G2,-G3, and-G4 isoforms transfected in a human melanoma cell line

B Riteau, P Moreau, C Menier… - Transplantation …, 2001 - academia.edu
THE NONCLASSICAL major histocompatibility com-plex molecule, HLA-G, is mainly
expressed on cytotrophoblast cells during pregnancy, 1 where it is likely involved in the …

Uveal melanoma: no expression of HLA-G

HMH Hurks, MM Valter, L Wilson… - … & visual science, 2001 - iovs.arvojournals.org
purpose. To investigate whether uveal melanoma cells express HLA-G, a nonclassical HLA
class I molecule that has been shown to be a critical mediator in the inhibition of natural …

Widespread expression of the nonclassical class I Qa-2 antigens in hemopoietic and nonhemopoietic cells

T Ungchusri, EY Chiang, G Brown, M Chen… - Immunogenetics, 2001 - Springer
We reexamined expression patterns of one of the best characterized mouse class Ib MHC
molecules, Qa-2. Transcripts encoding glycosylphosphatidylinositol-linked and soluble …

Characterization of a new HLA-G allele encoding a nonconservative amino acid substitution in the α3 domain (exon 4) and its relevance to certain complications in …

TVF Hviid, OB Christiansen… - …, 2001 - search.ebscohost.com
Cites a study on the characterization of a new HLA-G allele encoding, a nonconservative
amino acid substitution in the alpha3 domain. Protective effect of HLA-G against natural …

The multiple roles of major histocompatibility complex class-I-like molecules in mucosal immune function

RS Blumberg, Y van de Wal, S Claypool… - Acta odontologica …, 2001 - Taylor & Francis
The human major histocompatibility complex (MHC) on chromosome 6 encodes three
classical class-I genes: human leukocyte antigens (HLA) A, B, and C. These polymorphic …