P2X2, P2X2–2 and P2X5 receptor subunit expression and function in rat thoracolumbar sympathetic neurons

H Schädlich, K Wirkner, H Franke… - Journal of …, 2001 - Wiley Online Library
The present study investigated the pharmacological properties of excitatory P2X receptors
and P2X2 and P2X5 receptor subunit expression in rat‐cultured thoracolumbar sympathetic …

The role of purines in the peripheral nervous system

C Kennedy - Purinergic and Pyrimidinergic Signalling I: Molecular …, 2001 - Springer
The pioneering work on neurotransmission in the peripheral nervous system carried out
earlier in the century led to the widely accepted idea that noradrenaline (NA) was the sole …

Nucleoside and nucleotide transmission in sensory systems

GD Housley - Purinergic and Pyrimidinergic Signalling I: Molecular …, 2001 - Springer
Nucleotide and nucleoside signaling occurs via autocrine, paracrine, and neurotransmission
modes, mediated by P2 (nucleotide) and P1 (adenosine A 1–A 3) receptor transduction …

Cloned P2X receptor subunits in cerebellum and hippocampus

F Soto, ME Rubio - Drug development research, 2001 - Wiley Online Library
P2X receptor subunits have been found in the brain, with P2X2, P2X4, and P2X6 showing a
high level of expression. Here, we review the findings about the distribution of P2X receptor …

Ligand-gated purinergic receptors are differentially expressed in the adult rat vestibular periphery

JL Kreindler, M Troyanovskaya… - Annals of Otology …, 2001 - journals.sagepub.com
To further characterize the pattern of expression of the ligand-gated purinergic P2X
receptors in the peripheral vestibular system, we conducted reverse transcription …

Regulation of human P2X1 promoter activity by β helix–loop–helix factors in smooth muscle cells

PDK Dhulipala, EA Lianos, MI Kotlikoff - Gene, 2001 - Elsevier
We isolated and characterized genomic clones of the human P2X1 receptor (hP2X1) gene
in an effort to understand its tissue specific expression. The hP2X1 gene contains 12 exons …

P2X receptors

IP Chessell, AD Michel, PPA Humphrey - Purinergic and Pyrimidinergic …, 2001 - Springer
P2X receptors are a new sub-class of ligand-gated cation channels (Barnard and Humphrey
1998). Of the seven subunits cloned to date, all have a similar predicted topology, and are …

Effects of ATP on TTX-sensitive and TTX-resistant sodium currents in rat sensory neurons

JH Song, YK Shin, CS Lee, H Bang, M Park - Neuroreport, 2001 - journals.lww.com
Differential effects of ATP on tetrodotoxin-sensitive (TTX-S) and tetrodotoxin-resistant (TTX-
R) sodium currents in rat dorsal root ganglion neurons were studied using the whole-cell …

Mechanism of the inhibitory action of ATP in rat hippocampus

K Inoue, S Koizumi - Drug development research, 2001 - Wiley Online Library
We have already shown, by calcium imaging with an electrophysiological method and direct
detection of glutamate, that ATP inhibits the glutamate release from cultured rat …

Vasodilator responses to ATP and UTP are cAMP dependent in the mesenteric vascular bed of the cat

MK Shah, TJ Bivalacqua… - Journal of …, 2001 - journals.sagepub.com
Background: This study was designed to examine the responses to and the mechanism by
which purinergic agonists decrease vascular resistance in the mesenteric vascular bed of …