The Tol-Pal proteins of the Escherichia coli cell envelope: an energized system required for outer membrane integrity?

R Lloubès, E Cascales, A Walburger, E Bouveret… - Research in …, 2001 - Elsevier
The outer membrane of Gram-negative bacteria acts as a barrier against harmful lipophilic
compounds and larger molecules unable to diffuse freely through the porins. However, outer …

Molecular basis of bacterial outer membrane permeability revisited

H Nikaido - Microbiology and molecular biology reviews, 2003 - Am Soc Microbiol
Gram-negative bacteria characteristically are surrounded by an additional membrane layer,
the outer membrane. Although outer membrane components often play important roles in …

The Tol proteins of Escherichia coli and their involvement in the uptake of biomolecules and outer membrane stability

JC Lazzaroni, P Germon, MC Ray… - FEMS microbiology …, 1999 - academic.oup.com
Abstract The Tol proteins of Escherichia coli are involved in outer membrane stability. They
are also required for the uptake of the group A colicins and the translocation of filamentous …

Role of the carboxyl-terminal domain of TolA in protein import and integrity of the outer membrane

SK Levengood-Freyermuth, EM Click… - Journal of …, 1993 - Am Soc Microbiol
The TolA protein is involved in maintaining the integrity of the outer membrane of
Escherichia coli, as mutations in tolA cause the bacteria to become hypersensitive to …

How hydrophobic molecules traverse the outer membranes of Gram-negative bacteria

MC Wiener, PS Horanyi - Proceedings of the National …, 2011 - National Acad Sciences
The outer membrane (OM) of Gram-negative bacteria provides an effective barrier to their
often-harsh extracellular milieu. In particular, the outer leaflet of the OM is not a canonical …

The TolB protein interacts with the porins of Escherichia coli

A Rigal, E Bouveret, R Lloubes, C Lazdunski… - Journal of …, 1997 - Am Soc Microbiol
TolB is a periplasmic protein of the cell envelope Tol complex. It is partially membrane
associated through an interaction with the outer membrane lipoprotein PAL (peptidoglycan …

Proton motive force drives the interaction of the inner membrane TolA and outer membrane Pal proteins in Escherichia coli

E Cascales, M Gavioli, JN Sturgis… - Molecular …, 2000 - Wiley Online Library
The Tol–Pal system of the Escherichia coli envelope is formed from the inner membrane
TolQ, TolR and TolA proteins, the periplasmic TolB protein and the outer membrane Pal …

Touch and go: tying TonB to transport

K Postle, RJ Kadner - Molecular microbiology, 2003 - Wiley Online Library
Summary The TonB system of Gram‐negative bacteria appears to exist for the purpose of
transducing the protonmotive force energy from the cytoplasmic membrane, where it is …

The tonB gene of Serratia marcescens: sequence, activity and partial complementation of Escherichia coli tonB mutants

S Gaisser, V Braun - Molecular microbiology, 1991 - Wiley Online Library
The TonB protein plays a key role in the energy‐coupled transport of iron siderophores, of
vitamin B12, and of colicins of the B‐group across the outer membrane of Escherichia coli. In …

The Caulobacter Tol-Pal Complex Is Essential for Outer Membrane Integrity and the Positioning of a Polar Localization Factor

YC Yeh, LR Comolli, KH Downing, L Shapiro… - Journal of …, 2010 - Am Soc Microbiol
Cell division in Caulobacter crescentus involves constriction and fission of the inner
membrane (IM) followed about 20 min later by fission of the outer membrane (OM) and …