Brain is the most common site of metastatic spread in small-cell lung cancer (SCLC).
Approximately 10% of SCLC patients have brain metastases (BM) already at diagnosis and …

PURPOSE For decades the treatment of choice in small-cell lung cancer (SCLC) with brain
metastases has been corticosteroids and radiotherapy (RT) because of a presumed lack of …

Purpose The purpose of this study was to investigate the radiologic response of
asymptomatic brain metastases (BM) from small-cell lung cancer (SCLC) to first-line …

Brain metastasis is one of the most troublesome forms of metastatic disease in small cell
lung cancer and is seen in more than half of the patients during the course of their disease …

Background Small cell lung cancer (SCLC) accounts for approximately 20% of all cases of
lung cancer. It tends to disseminate early in the course of its natural history and to grow …

Brain metastases are a frequent complication in patients suffering from lung cancer, and a
significant cause of morbidity and mortality. Brain metastases are found in about 10% of …

Background During the 1980s reports describing the effect of systemic chemotherapy on
brain metastases from chemosensitive tumours emerged, including a few retrospective …

PURPOSE Brain metastasis occurs commonly in patients with small-cell lung cancer
(SCLC). Herein, we report the efficacy of irinotecan and carboplatin in the treatment of brain …

Purpose To establish an empirical systematic approach for the management of brain
metastases from a variety of cancers. Methods The English literature was reviewed from …

Central nervous system (CNS) me&stases are frequently seen in patients with small cell
lung cancer (SCLC)[11. The group of CNS metastases includes brain metastases, spinal …