During the last decade there has been an explosive increase in the knowledge of basic pain
physiology, but the implications for clinical practice have been less substantial. Despite …

Despite advances in our understanding of the pathophysiology of acute postoperative pain
and the pharmacology of analgesic drugs, postoperative pain is not always effectively …

It is impossible to accurately predict how much pain a patient will experience after an
operation or how much analgesic medication will be required to provide adequate pain …

Systemic application of analgesics is still the most frequently used method of postoperative
relief of pain. However, neither intermittent intramuscular nor intermittent intravenous …

Pain is a common problem in the early postoperative period. Techniques that provide
perioperative analgesia to alleviate pain may have a significant effect on postoperative …

Postoperative pain relief is only apparently an easy task. A brief survey of literature
investigating the discomfort experienced in the postoperative phase is all but encouraging …

There are many reasons for the inadequate treatment of postoperative pain. Doctors mostly
delegate pain relief to the nursing staff, who are overloaded with work. As a consequence …

Fourteen patients with postoperative pain were allowed to self‐administer preset doses of
pethidine intravenously via a logic‐controlled motor syringe. Plasma samples were collected …

Drug delivery by target-controlled infusion (TCI) allows automatic adjustments of the infusion
rate of a drug to maintain a desired target concentration. Since drug effect is more closely …

Patient-controlled analgesia (PCA) is one of the newer techniques for pain management. It
was developed in reaction to the large number of unsatisfied postoperative patients suffering …