A large body of immunologic, epidemiologic, and genetic data indicate that tissue inury in
multiple sclerosis (MS) results from an abnormal immune response to one or more myelin …

Multiple sclerosis (MS) is a debilitating immunological and neurodegenerative disorder.
Epidemiological studies have provided overwhelming evidence of complex genetic …

Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system
(CNS), the clinical course of which varies considerably between patients. Genetic complexity …

A large body of immunologic, epidemiologic, and genetic data indicate that tissue injury in
multiple sclerosis (MS) results from an abnormal immune response to one or more myelin …

Recent studies have better defined the association between the human leukocyte antigen
(HLA)-DR, cytotoxic T-lymphocyte antigen-4, interleukin-7 receptor, and interferon-gamma …

Multiple sclerosis (MS) is characterized by chronic inflammation and demyelination in the
central nervous system (CNS). Although the etiology of MS is unknown, both genetic and …

Multiple sclerosis (MS), the prototypic demyelinating disease in humans, is the most
common cause of acquired neurological dysfunction arising between early to mid adulthood …

The increased recurrence risk within families indicates a role for genetic factors in the
etiology of multiple sclerosis. Genes may influence susceptibility to the development of …

The etiology of multiple sclerosis is linked to a variety of genetic and environmental factors.
Both cell-mediated and humoral immune responses, triggered by extraneous or …

Multiple sclerosis (MS) clusters with the so-called complex genetic diseases, a group of
common disorders characterized by modest disease risk heritability and multifaceted gene …