We aimed to investigate the dynamics of the NF-κB signaling pathway in living cells using
GFP variants of p65-NF-κB, IκBα, tumor necrosis factor-receptor associated factor 2 (TRAF2) …

Although cytokine‐induced nuclear factor kb (nf‐κb) pathways are involved in muscle
wasting subsequent to disease, their potential role in disuse muscle atrophy has not been …

Activation of the nuclear factor (NF)-κB transcription complex by signals derived from the
surface expressed B cell antigen receptor controls B cell development, survival, and …

RelB mediates the constitutive nuclear pool of NF-κB transcriptional activity in myeloid and
lymphoid cells, which is believed to be secondary to its weak interaction with the classical …

The IKKβ and NEMO/IKKγ subunits of the NF-κB-activating signalsome complex are known
to be essential for activating NF-κB by inflammatory and other stress-like stimuli. However …

NF-κB essential modifier (NEMO), also known as IKK-γ, is a member of the I-κB kinase
complex responsible for phosphorylating I-κB, allowing the release and activation of NF-κB …

Proinflammatory activation of NF-κB requires an upstream kinase complex (IκB-kinase; IKK)
composed of two catalytic subunits (IKKα and IKKβ) and a noncatalytic regulatory …

The aryl hydrocarbon (Ah) receptor mediates most of the toxic effects induced by 2, 3, 7, 8-
tetrachlorodibenzo-p-dioxin (TCDD) and related compounds, which are ubiquitous …

Nuclear factor (NF)-κB proteins play crucial roles in immune responses and cellular survival.
Activation of NF-κB is mediated by the IκB kinase (IKK) complex, which is composed of two …

Canonical activation of NF-κB is mediated via phosphorylation of the inhibitory IκB proteins
by the IκB kinase complex (IKK). IKK is composed of a heterodimer of the catalytic IKKα and …