African swine fever virus (ASFV) encodes a homologue of the inhibitor of apoptosis (IAP)
that promotes cell survival by controlling the activity of caspase-3. Here we show that ASFV …

African swine fever virus (ASFV) A224L is a member of the inhibitor of apoptosis protein
(IAP) family. We have investigated the antiapoptotic function of the viral IAP both in stably …

Activation of the nuclear factor κB plays a key role in viral pathogenesis, resulting in
inflammation and modulation of the immune response. We have previously shown that …

Cytokines stimulate inflammatory defenses against viral infections. In order to evade host
defenses, viruses have developed strategies to counteract antiviral cytokines. African swine …

African swine fever virus (ASFV) is a large DNA virus that replicates predominantly in the cell
cytoplasm and is the only member of the Asfarviridae family. The virus causes an acute …

Certain viruses have evolved mechanisms to counteract innate immunity, a host response in
which nuclear factor κB (NF-κB) transcription factors play a central role. African swine fever …

An African swine fever virus (ASFV) gene with similarity to the cellular inhibitor of NFκB (IκB)
was described in the pathogenic African isolate Malawi Lil-20/1 (ORF 5EL) and a cell-culture …

Genes modulating apoptosis are encoded by many viruses and have an important role in
viral evasion mechanisms. Our objective was to characterize the expression of the IAP …

The analysis of the complete nucleotide sequence of the African swine fever virus genome
has revealed the existence of a number of genes potentially capable of modifying the host's …

An African swine fever virus (ASFV) gene with similarity to viral and cellular inhibitor of
apoptosis genes (iap) has been described in the African isolate Malawi Lil-20/1 (ORF 4CL) …