[图书][B] Mechanistic studies to elucidate the role of lipid vehicles on solubility, formulation and bioavailability of poorly soluble compounds
I Dumanli - 2002 - search.proquest.com
Lipids have been used to improve the bioavailability of poorly soluble drugs for almost
twenty years. However, they are still not well characterized. There are limited publications …
twenty years. However, they are still not well characterized. There are limited publications …
What determines drug solubility in lipid vehicles: is it predictable?
SS Rane, BD Anderson - Advanced drug delivery reviews, 2008 - Elsevier
Lipid-based drug delivery systems are of increasing interest to the pharmaceutical scientist
because of their potential to solubilize drug molecules that may be otherwise difficult to …
because of their potential to solubilize drug molecules that may be otherwise difficult to …
[HTML][HTML] Fundamental aspects of lipid-based excipients in lipid-based product development
Poor aqueous solubility of drugs is still a foremost challenge in pharmaceutical product
development. The use of lipids in designing formulations provides an opportunity to …
development. The use of lipids in designing formulations provides an opportunity to …
Lipid-based formulations for oral administration of poorly water-soluble drugs
Lipid-based drug delivery systems have shown great potentials in oral delivery of poorly
water-soluble drugs, primarily for lipophilic drugs, with several successfully marketed …
water-soluble drugs, primarily for lipophilic drugs, with several successfully marketed …
Functions of lipids for enhancement of oral bioavailability of poorly water-soluble drugs
BK Nanjwade, DJ Patel, RA Udhani, FV Manvi - Scientia pharmaceutica, 2011 - mdpi.com
Lipid-based formulations encompass a diverse group of formulations with very different
physical appearance, ranging from simple triglyceride vehicles to more sophisticated …
physical appearance, ranging from simple triglyceride vehicles to more sophisticated …
Lipid–an emerging platform for oral delivery of drugs with poor bioavailability
The sole objective of pharmaceutical science is to design successful dosage forms which
fulfill the therapeutic needs of the patients effectively. Development of new drug entities is …
fulfill the therapeutic needs of the patients effectively. Development of new drug entities is …
[HTML][HTML] Exploring LIPID's for their Potential to Improves bioavailability of lipophilic drugs candidates: a review
S Sambhakar, R Saharan, S Narwal, R Malik… - Saudi Pharmaceutical …, 2023 - Elsevier
This review aims to provide a thorough examination of the benefits, challenges, and
advancements in utilizing lipids for more effective drug delivery, ultimately contributing to the …
advancements in utilizing lipids for more effective drug delivery, ultimately contributing to the …
Mechanisms of drug solubilization by polar lipids in biorelevant media
V Katev, Z Vinarov, S Tcholakova - European Journal of Pharmaceutical …, 2021 - Elsevier
Despite the widespread use of lipid excipients in both academic research and oral
formulation development, rational selection guidelines are still missing. In the current study …
formulation development, rational selection guidelines are still missing. In the current study …
Critical In Vitro Characterization Methods of Lipid-Based Formulations for Oral Delivery: a Comprehensive Review
NK Swarnakar, N Venkatesan, G Betageri - Aaps Pharmscitech, 2019 - Springer
Lipids have been extensively used in formulations to enhance dissolution and bioavailability
of poorly water-soluble as well as water-soluble drug molecules. The digestion of lipid …
of poorly water-soluble as well as water-soluble drug molecules. The digestion of lipid …
[HTML][HTML] Recent advances in lipid-based formulation technology
Lipid-based formulations encompass a wide variety of delivery modes and technologies,
ranging from immediate release to sustained release formulations, from liquids to semi …
ranging from immediate release to sustained release formulations, from liquids to semi …