[图书][B] The sodium (+)/potassium (+)-ATPase as a signal transducer
MS Haas - 2002 - search.proquest.com
Binding of ouabain to the Na+/K+-ATPase activates tyrosine phosphorylation of the EGFR,
Src, and MAPK in both cardiac myocytes and A7r5 cells. We explored the roles of Src and …
Src, and MAPK in both cardiac myocytes and A7r5 cells. We explored the roles of Src and …
[HTML][HTML] Src-mediated inter-receptor cross-talk between the Na+/K+-ATPase and the epidermal growth factor receptor relays the signal from ouabain to mitogen …
M Haas, H Wang, J Tian, Z Xie - Journal of Biological Chemistry, 2002 - ASBMB
Binding of ouabain to Na+/K+-ATPase activates tyrosine phosphorylation of the epidermal
growth factor receptor (EGFR), Src, and p42/44 mitogen-activated protein kinases (MAPKs) …
growth factor receptor (EGFR), Src, and p42/44 mitogen-activated protein kinases (MAPKs) …
Signal-transducing function of Na+-K+-ATPase is essential for ouabain's effect on [Ca2+]i in rat cardiac myocytes
We showed before that Na+-K+-ATPase is also a signal transducer in neonatal rat cardiac
myocytes. Binding of ouabain to the enzyme activates multiple signal pathways that regulate …
myocytes. Binding of ouabain to the enzyme activates multiple signal pathways that regulate …
[HTML][HTML] Involvement of Src and epidermal growth factor receptor in the signal-transducing function of Na+/K+-ATPase
M Haas, A Askari, Z Xie - Journal of Biological Chemistry, 2000 - ASBMB
Nontoxic concentrations of ouabain, causing partial inhibition of the cardiac myocyte Na+/K+-
ATPase, induce hypertrophy and several growth-related genes through signal pathways that …
ATPase, induce hypertrophy and several growth-related genes through signal pathways that …
[HTML][HTML] Ouabain interaction with cardiac Na+/K+-ATPase initiates signal cascades independent of changes in intracellular Na+ and Ca2+ concentrations
We have shown previously that partial inhibition of the cardiac myocyte Na+/K+-ATPase
activates signal pathways that regulate myocyte growth and growth-related genes and that …
activates signal pathways that regulate myocyte growth and growth-related genes and that …
Ouabain interaction with cardiac Na/K-ATPase reveals that the enzyme can act as a pump and as a signal transducer.
Z Xie - Cellular and molecular biology (Noisy-le-Grand …, 2001 - europepmc.org
Na/K-ATPase hydrolyzes ATP to maintain the transmembrane gradients of Na+ and K+
found in most mammalian cells and is inhibited specifically by cardiac glycosides such as …
found in most mammalian cells and is inhibited specifically by cardiac glycosides such as …
Relation of the sodium (+)/potassium (+)-ATPase to reactive oxygen species and mitogen-activated protein kinases
AM Bair - 2002 - search.proquest.com
Ouabain and other cardiac glycosides are specific inhibitors of the Na+/K+-ATPase, an
enzyme that catalyzes the active transport of Na+ and K+ across the plasma membrane of …
enzyme that catalyzes the active transport of Na+ and K+ across the plasma membrane of …
Cell Signaling Associated with Na+/K+-ATPase: Activation of Phosphatidylinositide 3-Kinase IA/Akt by Ouabain Is Independent of Src
J Wu, EE Akkuratov, Y Bai, CM Gaskill, A Askari… - Biochemistry, 2013 - ACS Publications
Exposure of intact cells to selective inhibitors of Na+/K+-ATPase such as ouabain activates
several growth-related cell signaling pathways. It has been suggested that the initial event of …
several growth-related cell signaling pathways. It has been suggested that the initial event of …
[PDF][PDF] Na/K-ATPase and Signal Transduction
H Wang - 2005 - etd.ohiolink.edu
Na+/K+-ATPase, or sodium pump, is a ubiquitous transmembrane enzyme that has long
been ascribed the function of transporting Na+ and K+ across the plasma membrane …
been ascribed the function of transporting Na+ and K+ across the plasma membrane …