The plasminogen system has been implicated in clot lysis, wound healing, tissue
regeneration, cancer and many other processes that affect health and disease. The …

Plasma membrane urokinase-type plasminogen activator (uPA)-receptor (uPAR) is a GPI-
anchored protein that binds with high-affinity and activates the serine protease uPA, thus …

In a variety of cell types, the glycolipid-anchored urokinase receptor (uPAR) is colocalized
pericellularly with components of the plasminogen activation system and endocytosis …

Urokinase-type plasminogen activator receptor (uPAR) binds the urokinase-type
plasminogen activator (uPA) and facilitates a proteolytic cascade focused at the cell surface …

Proteolysis is a key event in several biological processes; proteolysis must be tightly
controlled because its improper activation leads to dramatic consequences. Deregulation of …

The urokinase plasminogen activator receptor (uPAR) mediates cell motility and tissue
remodeling. Although uPAR may be expressed transiently in many tissues during …

The urokinase-mediated plasminogen activation (PA) system is involved in many
physiological and pathological events that include cell migration and tissue remodelling …

Urokinase-type plasminogen activator receptor (uPAR) expression is elevated during
inflammation and tissue remodelling and in many human cancers, in which it frequently …

Urokinase-type plasminogen activator (uPA) and its receptor (uPAR) participate in matrix
degradation and cell migration by focusing proteolysis and functioning as a signaling …

The urokinase plasminogen activator receptor (uPAR) has been implicated in the growth,
metastasis, and angiogenesis of several solid and hemotologic malignancies. uPAR is part …