Successful blood and marrow transplant (BMT), both autologous and allogeneic, requires
the infusion of a sufficient number of hematopoietic progenitor/stem cells (HPCs) capable of …

Abstract α‐chemokines, which control the activation and directed migration of leukocytes,
participate in the inflammatory processes in host defense response. One of the α …

Abstract CXC ligand 12 (CXCL12; also known as stromal cell–derived factor 1α/SDF-1α)
chemoattracts hematopoietic stem and progenitor cells (HSCs/HPCs) and is thought to play …

T cells may encounter glutamate, the major excitatory neurotransmitter in the nervous
system, when patrolling the brain and in glutamate-rich peripheral organs. Moreover …

Complement has recently been implicated in developmental pathways and noninflammatory
processes. The expression of various complement components and receptors has been …

OBJECTIVE: Administration of granulocyte colony-stimulating factor (G-CSF) results in the
mobilization of hematopoietic progenitor and stem cells from the bone marrow into the …

The chemokine, stromal derived factor-1 (SDF1) has been shown to modulate the homing of
stem cells to its site by mediating chemotaxis. We demontrated overexpression of SDF-1 …

OBJECTIVE: In spite of the wide usage of mobilized peripheral blood hematopoietic stem
and progenitor cells (HSC/HPC) for transplantation, the mechanism of granulocyte colony …

Mobilization into peripheral blood of bone marrow-derived cells including hematopoietic
stem cells (HSCs) and endothelial progenitor cells (EPCs), is regulated by …

The pathogenesis of B-cell chronic lymphocytic leukemia (B-CLL) has been linked to an
overexpression of the chemokine receptor CXCR4 and increased in vitro functional …