Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo
D Skokos, HG Botros, C Demeure, J Morin… - The Journal of …, 2003 - journals.aai.org
Mast cells (MCs) are considered major players in IgE-mediated allergic responses, but have
also recently been recognized as active participants in innate as well as specific immune …
also recently been recognized as active participants in innate as well as specific immune …
Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes
D Skokos, S Le Panse, I Villa, JC Rousselle… - The Journal of …, 2001 - journals.aai.org
Mitogenic activity of bone marrow-derived mouse mast cells and mast cell lines P815 and
MC/9 on B and T lymphocytes is present in their culture supernatants. To identify this activity …
MC/9 on B and T lymphocytes is present in their culture supernatants. To identify this activity …
Mature dendritic cells secrete exosomes with strong ability to induce antigen-specific effector immune responses
E Segura, S Amigorena, C Théry - Blood Cells, Molecules, and Diseases, 2005 - Elsevier
Exosomes are secreted vesicles formed in late endocytic compartments. Immature dendritic
cells (DCs) secrete exosomes which transfer functional MHC–peptide complexes to other …
cells (DCs) secrete exosomes which transfer functional MHC–peptide complexes to other …
Exosomes bearing HLADR1 molecules need dendritic cells to efficiently stimulate specific T cells
H VincentSchneider… - International …, 2002 - academic.oup.com
Abstract Exosomes are small vesicles (60–100 nm) secreted by various cell types upon the
fusion of endosomal compartments with the plasma membrane. Exosomes from antigen …
fusion of endosomal compartments with the plasma membrane. Exosomes from antigen …
Molecular characterization of dendritic cell-derived exosomes: selective accumulation of the heat shock protein hsc73
C Théry, A Regnault, J Garin, J Wolfers… - The Journal of cell …, 1999 - rupress.org
Exosomes are membrane vesicles secreted by hematopoietic cells upon fusion of late
multivesicular endosomes with the plasma membrane. Dendritic cell (DC)-derived …
multivesicular endosomes with the plasma membrane. Dendritic cell (DC)-derived …
[HTML][HTML] Mast cell synapses and exosomes: membrane contacts for information exchange
A Carroll-Portillo, Z Surviladze, A Cambi… - Frontiers in …, 2012 - frontiersin.org
In addition to their central role in allergy, mast cells are involved in a wide variety of cellular
interactions during homeostasis and disease. In this review, we discuss the ability of mast …
interactions during homeostasis and disease. In this review, we discuss the ability of mast …
[HTML][HTML] Exogenous and endogenous dendritic cell-derived exosomes: Lessons learned for immunotherapy and disease pathogenesis
M Elashiry, R Elsayed, CW Cutler - Cells, 2021 - mdpi.com
Immune therapeutic exosomes, derived exogenously from dendritic cells (DCs), the
'directors' of the immune response, are receiving favorable safety and tolerance profiles in …
'directors' of the immune response, are receiving favorable safety and tolerance profiles in …
Mast cellderived exosomes promote Th2 cell differentiation via OX40LOX40 ligation
F Li, Y Wang, L Lin, J Wang, H Xiao, J Li… - Journal of …, 2016 - Wiley Online Library
Exosomes are nanovesicles released by different cell types, such as dendritic cells (DCs),
mast cells (MCs), and tumor cells. Exosomes of different origin play a role in antigen …
mast cells (MCs), and tumor cells. Exosomes of different origin play a role in antigen …
Indirect activation of naïve CD4+ T cells by dendritic cell–derived exosomes
C Théry, L Duban, E Segura, P Véron, O Lantz… - Nature …, 2002 - nature.com
Dendritic cells (DCs) secrete vesicles of endosomal origin, called exosomes, that bear major
histocompatibility complex (MHC) and T cell costimulatory molecules. Here, we found that …
histocompatibility complex (MHC) and T cell costimulatory molecules. Here, we found that …
Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells
AE Morelli, AT Larregina, WJ Shufesky, MLG Sullivan… - Blood, 2004 - ashpublications.org
Exosomes are nanovesicles released by leukocytes and epithelial cells. Although their
function remains enigmatic, exosomes are a source of antigen and transfer functional major …
function remains enigmatic, exosomes are a source of antigen and transfer functional major …