Previous studies in the Hildreth laboratory determined that the expression of VCAM-1 in the
erythroleukemic cell line K562 caused susceptibility to HTL-V-1-induced syncytium …

We have previously shown that erythroleukemia cells (K562) transfected with vascular
adhesion molecule 1 (VCAM-1) are susceptible to human T-cell leukemia virus type 1 (HTLV …

Cholesterol-rich plasma membrane microdomains are important for entry of many viruses,
including retroviruses. Depletion of cholesterol with 2-hydroxypropyl-β-cyclodextrin inhibits …

The human T-cell leukemia virus type 1 (HTLV-1) envelope protein is required for virus
spread. This study further characterizes the role of the envelope protein in HTLV-1 …

HTLV-1 p12 is an endoplasmic reticulum resident protein that is cleaved to generate p8,
which traffics to the cell surface. p12 promotes T-cell activation by increasing NFAT activity …

Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic retrovirus that is the causative
infectious agent of adult T-cell leukemia/lymphoma (ATL), an aggressive and fatal CD4+ T …

Three molecules have been identified as the main cellular factors required for binding and
entry of human T-cell leukemia virus type 1 (HTLV-1): glucose transporter 1 (GLUT1) …

ABSTRACT Alpha-2a interferon (IFN-α2a) has beneficial clinical effects on human T-cell
leukemia virus type 1 (HTLV-1) infection, but its antiviral mechanism of action is unknown …

To mediate intercellular communication, cells produce extracellular vesicles (EVs). These
EVs transport many biomolecules such as proteins, nucleic acids, and lipids between cells …