Estrogen attenuates neural damage resulting from a variety of experimental injury models in
adult female rats. To determine whether estrogens neuroprotective actions are age-specific …

Previous work from this lab has shown that estrogen attenuates inflammatory cytokine
production following brain lesions in young adult female rats, but not in older, reproductive …

Hormone therapy and estrogen therapy in postmenopausal women have been thought to
ameliorate cognitive dysfunction and decrease the risk and/or progress of …

Estrogen replacement therapy in postmenopausal women ameliorates cognitive dysfunction
and decreases the risk and/or severity of neurodegenerative conditions such as Alzheimer's …

Background Reproductive aging in females is characterized by fluctuations and precipitous
decline in estrogen levels, which may lead to reduction in cognitive function and age …

Evidence that estrogen protects neurons against toxic/ischemic insults or
degenerative/aging processes is evident in a variety of in vitro and in vivo systems …

We have shown that 17β-estradiol exerts profound protective effects against stroke-like
ischemic injury in female rats. These effects are evident using physiological levels of …

Estrogen replacement therapy is thought to attenuate the incidence of Alzheimer's disease
in women and enhance cognitive functions. In rodents, estrogen protects cerebral cortical …

Aging is associated with at least down-regulation of several cellular functions and
diminished responsiveness to internal and external signals, and possibly with direct cell …

Several clinical studies suggest that estradiol acts as a potent growth and protective factor in
the adult brain. Postmenopausal women experience permanent hypoestrogenicity and …