The mammalian alveolar epithelium is composed of alveolar type I (AT1) and alveolar type II
(AT2) cells that together coordinate tissue function. We used a heterocellular culture model …

The alveolar epithelium consists of two cell types, alveolar type I (AT1) and alveolar type II
(AT2) cells. We have recently shown that 7-day-old cultures of AT2 cells grown on a type I …

Inter-and extracellular-mediated changes in intracellular Ca2+ concentration ([Ca2+] i) can
ensure coordinated tissue function in the lung. Cultured rat alveolar epithelial cells (AECs) …

We analyzed the pattern of gap junction protein (connexin) expression in vivo by indirect
immunofluorescence. In normal rat lung sections, connexin (Cx) 32 was expressed by type II …

Recent observations suggest that cell-cell interactions may modulate the response of the
alveolar epithelium to injury. Expression and function of gap junctions were thus evaluated …

We examined phenotype-specific changes in gap junction protein [connexin (Cx)]
expression and function by cultured rat alveolar type II cells. Type II cells cultured on …

During homeostasis and in response to injury, alveolar type II (AT2) cells serve as progenitor
cells to proliferate, migrate, differentiate, and reestablish both alveolar type I (AT1) and AT2 …

Gap junction channels enable the direct flow of signaling molecules and metabolites
between cells. Alveolar epithelial cells show great variability in the expression of gap …

Background The alveolus in the lung tissue is an extremely vulnerable site. Alveolar
macrophages control this micro-environment both in states of health and illnesssuch as …

THE LUNG is a complex organ that contains at least 40 different varieties of cells. Different
types of pulmonary parenchymal cells were first identified based on their histological …