Cryptococcus neoformans is an opportunistic fungal pathogen with a defined sexual cycle in
which the α allele of the mating type locus is linked to virulence and haploid differentiation …

Cryptococcus neoformans is an opportunistic fungal pathogen with a defined sexual cycle
involving fusion of haploid MAT α and MAT a cells. Virulence has been linked to the mating …

Sexual identity and mating are linked to virulence of the fungal pathogen Cryptococcus
neoformans. Cells of the α mating type are more prevalent and can be more virulent than a …

Cryptococcus neoformans is a human fungal pathogen that undergoes a dimorphic
transition from a unicellular yeast to multicellular hyphae during opposite sex (mating) and …

Partial sequence analysis of the Cryptococcus neoformans MATα mating type locus
revealed the presence of a gene with substantial sequence similarity to other fungal mitogen …

The mitogen-activated protein kinase (MAPK) pathways control diverse cellular functions in
pathogenic fungi, including sexual differentiation, stress response, and maintenance of cell …

Gene duplication and divergence via both the loss and gain of gene activities are powerful
evolutionary forces underlying the origin of new biological functions. Here a comparative …

The Cryptococcus neoformans Ras1 signal transduction pathway controls mating, hyphal
differentiation, and the ability of this opportunistic human fungal pathogen to grow at …

Virulence in the human fungal pathogen Cryptococcus neoformans is associated with the α
mating type. Studies to identify the properties of α cells that enhance pathogenesis have led …

Cryptococcus neoformans is a fungal pathogen that causes meningitis in
immunocompromised hosts. The organism has a known sexual cycle, and strains of the …