We performed a prospective, international, observational study of 844 hospitalized patients
with blood cultures positive for Streptococcus pneumoniae. Fifteen percent of isolates had in …

The impact of penicillin susceptibility on medical outcomes for adult patients with bacteremic
pneumococcal pneumonia was evaluated in a retrospective cohort study conducted during …

Limited data are available about the impact of antimicrobial resistance on clinical outcomes
in cases of pneumococcal pneumonia. This was studied in 146 persons hospitalized with …

Introduction The cost-effectiveness of blood cultures in community-acquired pneumonia
(CAP) has been questioned. Although penicillin-resistant Streptococcus pneumoniae is an …

Background Penicillin-resistant strains of Streptococcus pneumoniae are now found
worldwide, and strains with resistance to cephalosporin are being reported. The appropriate …

We retrospectively studied 24 adults with bacteremic pneumonia (25 episodes) due to
penicillin-resistant pneumococci, for which the minimal inhibitory concentrations (MICs) of …

Background. The rate of in vitro bacterial resistance to antimicrobial agents is escalating
among pathogens that cause the most serious respiratory tract infections. Many reports …

Pneumococcal disease was studied prospectively to determine the risk factors associated
with resistance to penicillin and other antibiotics. One hundred twelve clinically significant …

Previous antibiotic exposure is one of the most important predictors for acquisition of
penicillin-nonsusceptible Streptococcus pneumoniae (PNSP) infection. To determine the …

Streptococcus pneumoniae strains have exhibited decreasing susceptibility to penicillins
and macrolides during the past several years. We reviewed the medical charts of all patients …